Searchable abstracts of presentations at key conferences in endocrinology

ea0035p118 | Calcium and Vitamin D metabolism | ECE2014

The relationship with plasma calcium levels, metabolic syndrome, and risk parameters in overweight and obese Turkish women

Ipek Emel , Ucer Mehtap , Cikim Ayse , Tanyolac Sinan

Introduction: Obesity prevalance is rapidly increasing all over the world and become a serious health problem. There is a significant correlation between serum calcium levels and body fat mass. It was indicated that when plasma calcium levels increase, BMI decrease however, insulin, total cholesterol, and triglycerides levels increase. In this study, it was investigated the relationship between plasma calcium levels and cardiovascular risk factors and metabolic syndrome parame...

ea0020p473 | Obesity and Metabolism | ECE2009

Association between platelet count and metabolic risk factors in over weight and obese women

Kutluturk Faruk , Tanyolac Sinan , Azezli Adil , Orhan Yusuf

Introduction: We aimed to evaluate the relationship between platelet count and metabolic risk factors in over weight and obese women in Turkish women.Methods: Over weight (BMI>25 kg/m2) 665 and obese (BMI>30 kg/m2) 4609 women were enrolled into the study. The patients were divided into three group according to the platelet count (PLT), Group I (n=1724) consist of serum PLT≤245×103, group II (n...

ea0011p319 | Diabetes, metabolism and cardiovascular | ECE2006

Effects of Ezetimibe on serum lipoproteins in patients with homozygous familial hypercholesterolemia undergoing LDL cholesterol apheresis and high dose atorvastatin therapy

Azezli A , Bayraktaroglu T , Kutluturk F , Cikim A , Tanyolac S , Orhan Y

Homozygous familial hypercholesterolemia (HoFH) represents a potentially fatal condition that is caused by low density lipoprotein (LDL) cholesterol receptor deficiency. Statins alone are not effective in HoFH. In recent years, semiselective or selective LDL cholesterol apheresis systems have been shown to prolong life. However, applying LDLC apheresis therapy, recent evidence also suggests that more intense LDL cholesterol reduction is associated with more clinical benefit. E...

ea0011p320 | Diabetes, metabolism and cardiovascular | ECE2006

Effect of micronised fenofibrate on plasma levels of c-reactive protein in combined hyperlipidemia

Azezli A , Bayraktaroglu T , Kutluturk F , Cikim A , Tanyolac S , Orhan Y

C-reactive protein (CRP) is a non-specific but sensitive marker of underlying systemic inflammation. High CRP levels correlate with risk for future cardiovascular events. Statins can lower the circulating levels of CRP. In contrast, the evidence that fibrates lower CRP levels is very limited. This retrospective study evaluates the effect of micronised fenofibrate on plasma levels of CRP in patients with combined hyperlipidemia.Sixty-four patients with co...

ea0011p600 | Neuroendocrinology and behaviour | ECE2006

Pulmonary function in Cushing’s disease

Bayraktaroglu T , Kutluturk F , Turan E , Orhan Y , Tanyolac S

Numerous clinical manifestations have been described in association with Cushing’s disease (CD). There was no eligible data on pulmonary function tests in CD patients. We aimed to assess pulmonary function test included spirometry in a series of patients with active Cushing’s disease (2 men, 9 women). Mean age, height, weight, body mass index were 36.7±12.6 (range 22–63 years), 156.9±8.4 cm, 74.1±10.7 kg, 29.6±3.8 kg/m2, respective...

ea0011p861 | Thyroid | ECE2006

The use of konjac glucomannan to lower serum thyroid hormones in hyperthyroidism

Bayraktaroglu T , Kutluturk F , Azezli A , Orhan Y , Tanyolac S

Objective: Patients with hyperthyroidism occasionally need rapid restoration to the euthyroid state. In wiew of the increased enterohepatic circulation of thyroxine (T4) and triiodothyronine (T3) in thyrotoxicosis, and metabolic effects of konjac glucomannan in gastrointestinal system, we aimed to determine the activity of glucomannan in treatment of hyperthyroidism.Methods: A prospective, randomized, placebo-controlled, one-blind study design was used w...

ea0011p321 | Diabetes, metabolism and cardiovascular | ECE2006

Long term safety of Atorvastatin and Fenofibrate therapy in patients with combined hyperlipidemia

Azezli A , Telci A , Bayraktaroglu T , Cikim A , Uzum A , Kutluturk F , Tanyolac S , Orhan Y

Combined hyperlipidemia is characterized by elevated levels of total cholesterol, low density lipoprotein (LDL), triglyceride and mild decrease in high density lipoprotein (HDL) cholesterol. It is difficult to achieve desirable decreases of LDL cholesterol, triglycerides and increasing of HDL cholesterol with monotherapy in patients with mixed hyperlipoproteinemia. This retrospective study was carried out to assess the safety atorvastatin-fenofibrate combination therapy.<p...

ea0011p463 | Endocrine tumours and neoplasia | ECE2006

An intrasellar germinoma with normal cerebrospinal fluid β-HCG concentration misdiagnosed as hypophysitis

Tanyolac Sinan , Cikim Ayse , Ozbey Nese , Sencer Altay , Kurt Ramaza , Sencer Serra , Turantan Inan , Molvalilar Senay

Intracranial germinomas are malignant neoplasms which are supposed to arise from primitive germ cells failed to migrate to the genital crest during embryonic development. Most of them are located in the intra-suprasellar region and may cause anterior and particularly posterior pituitary hormone deficits. Early establishment of the histological diagnosis is important for optimum treatment planning and a successful outcome. Intracranial germinomas are radiosensitive and potentia...

ea0011p673 | Reproduction | ECE2006

Oxidized low-density lipoprotein autoantibodies in patients with polycystic ovary syndrome

Azezli A , Telci A , Bayraktaroglu T , Kutluturk F , Uzum A , Cikim A , Tanyolac S , Orhan Y

Polycystic ovary syndrome (PCOS), affects approximately 5% to 10% all women. Insulin resistance is highly associated with this syndrome. Insulin resistance is associated with increased oxidation of low density lipoprotein (LDL) cholesterol. Oxidized LDL autoantibody levels are generally measured to evaluate the degree of LDL oxidation. In the present study, we aimed to measure serum titers of oxidized LDL autoantibodies in patients with PCOS.Twenty-five ...