Searchable abstracts of presentations at key conferences in endocrinology

ea0083domnp1 | Diabetes, Obesity, Metabolism and Nutrition | EYES2022

Does phase angle analysis in overweight women be a surrogate marker of insulin resistance?

G Erta , G Gersone , P Tretjakovs

Background: Phase angle (PA) is defined as the angular displacement between the current and voltage waveforms due to capacitor interference, measured in degrees or radians. [1] The fat-free mass (FFM) is made up of water and electrolytes and is characterized by a low impedance, while the FM (fat mass) is water-free and, therefore, with a high impedance. The larger the FM, the higher the resistance, and this parameter affects the PA. Body mass index (BMI) is the most widely use...

ea0016p719 | Thyroid | ECE2008

Alterations of the circulating selectin, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 in patients with non-immune nodular thyroid disease

Ducena Kristine , Tretjakovs Peteris , Jurka Antra , Bormane Inga , Pirags Valdis

Cytokines, including adhesion molecules, are a family of protein mediators that are important in transducing information between various cell types, were non-immune cells may also be important sources of certain cytokines.Aim: Aim of this study was to evaluate of soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1 (sVCAM-1), and soluble E-selectin (sE-selectin) in patients with non-immune nodular thyroid disease...

ea0011p340 | Diabetes, metabolism and cardiovascular | ECE2006

Decreased cutaneous vasomotor responses in patients with insulin resistance

Tretjakovs P , Jurka A , Geldenere K , Stifts A , Aivars JI , Pirags V

Aim: To evaluate the relationship between insulin resistance and cutaneous vasomotor responses (endothelial-dependent vasodilatation and peripheral sympathetic failure: noradrenergic control of smooth muscle cells – vasoconstriction and neuropeptides induced vasodilatation) in patients with metabolic syndrome (MS).Methods and subjects: Patients with insulin resistance and MS (defined according to ‘The 2005 IDF definition of the metabolic syndro...

ea0002p30 | Diabetes and metabolism | SFE2001

CUTANEOUS VASOMOTOR RESPONSE IN PATIENTS WITH MICROALBUMINURIA

Stifts A , Tretjakovs P , Martinsons A , Petersons A , Jurka A , Marga M , Pirags V

According to the hypothesis, the capillary albumin leakage parallels the degree of microalbuminuria, probably reflecting a generalized basement membrane abnormality, and relates with microvascular disfunction. The AIM of our study was to estimate postocclusive reactive hyperaemic response in patients with microalbuminuria. MATERIALS: Patients with microalbuminuria were divided into two groups: 18 patients with diabetic nephropathy (N) and 18 non-diabetic patients with glomerul...

ea0022p157 | Cardiovascular endocrinology and lipid metabolism | ECE2010

Alterations of plasminogen activator inhibitor-1, myeloperoxidase and matrix metalloproteinase-9 in coronary artery disease patients with type-2 diabetes mellitus

Tretjakovs Peteris , Jurka Antra , Bormane Inga , Bahs Guntis , Cirule Kristine , Martinsons Agris , Verbovenko Jurijs , Pirags Valdis

Aim: To evaluate alterations in plasminogen activator inhibitor-1 (PAI-1), myeloperoxidase (MPO) and matrix metalloproteinase-9 (MMP-9) levels, and their relation to insulin resistance (IR) in coronary artery disease (CAD) patients with stable and unstable angina with and without type-2 diabetes mellitus (T2DM).Patients and methods: CAD patients were recruited into four groups: 16 CAD patients with stable angina and T2DM (SD); 16 CAD patients with stable...

ea0020p488 | Obesity and Metabolism | ECE2009

Vasomotor dysfunction and alterations of adipokines in metabolic syndrome patients with insulin resistance

Tretjakovs Peteris , Jurka Antra , Bormane Inga , Reihmane Dace , Mikelsone Indra , Balode Liga , Aivars Juris , Pirags Valdis

Aim: To evaluate relationships between adipokines (adiponectin, resistin, leptin, interleukin-6, tumor necrosis factor-alpha), insulin resistance and cutaneous vasomotor responses in metabolic syndrome (MS) patients with insulin resistance. MS patients with insulin resistance were divided into two groups: 18 patients with type-2 diabetes mellitus (without insulin therapy and pronounced diabetic complications) (DM) and 18 patients without DM. Of 18 healthy subjects were selecte...

ea0056p461 | Diabetes complications | ECE2018

Markers of nitrosative stress, angiogenesis and inflammation linked to severity of complications in type 1 diabetes

Sokolovska Jelizaveta , Osina Kristine , Dekante Alise , Krievina Gita , Tretjakovs Peteris , Pirags Valdis , Sjakste Nikolajs

Background: Hypoxia, oxidative stress and inflammation induced by hyperglycaemia are ‘key players’ in development of diabetic complications.Aim: To analyze differences in levels of nitric oxide (NO) and its metabolites nitrate and nitrite (NO2/NO3) and well as angiopoietin 2 (Ang2) and neuropeptide Y (NPY) in patients with type 1 diabetes and different complications status; to analyze associations between these markers.Me...