Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep302 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Effects of glucagon-like peptide 1 analogue on eating behavior in patients with obesity

Logvinova Oksana , Troshina Ekaterina

Introduction: One of the objectives of weight loss in obesity is to prevent metabolic disorders. An important component in the maintenance of the achieved results is a change of eating behavior.Goal: To study the effect of liraglutide 3.0 mg on the dynamics of metabolic parameters and eating behavior in patients with obesity.Materials and methods: The study enrolled 42 obese patients in whom anthropometric parameters, metabolic par...

ea0070aep312 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Combination of baseline body weight with active plasma ghrelin level could predict early response with liraglutide 3.0 mg in patients with obesity

Logvinova Oksana , Troshina Ekaterina

Introduction: Liraglutide 3.0 mg could be effective option for obesity management. It is known that patients who have ≥5% weight loss in 16 weeks (‘early responders’ (ERs)) will have ≥10% weight loss in 56 weeks [1]. Predictors of this early response (ER) in 16 weeks are unknown.Methods: 22 obese patients (30% men; median age 40.0 [33.0; 48.5]) were recruited. The exclusion criteria were diabetes, psychotic disorders, obesity due ...

ea0011p854 | Thyroid | ECE2006

The research of IQ level in school children who live in the regions with iodine deficiency

Slovjeva SI , Troshina A , Zhukov AO

Purpose: To evaluate the level of intellect according to tests data in the regions with iodine deficiency.Methods: In the frame the ‘Thyromobil’ project that was held during 2003-2005y in 18 regions of Russian Federation were done standartized epidemiologic research. The research included clinical examination, palpation thyroid, ultrasonic examination of thyroid, definitions of ioduria. We used Cattell test, free of cultural influence (Culture ...

ea0081ep23 | Adrenal and Cardiovascular Endocrinology | ECE2022

Determination of 18-hydroxycortisol, 18-oxocortisol by HPLC–MS/MS in the differential diagnosis of various forms of primary aldosteronism

Romanova Natalia , Platonova Nadezhda , Troshina Ekaterina

Introduction: Aldosterone synthase participates in the key reactions of aldosterone synthesis – 11-hydroxylation, 18-hydroxylation and, finally, 18-oxidation. In recent works devoted to evaluating the effectiveness of hybrid steroids in the differential diagnosis of subtypes of primary aldosteronism (PA), it is worth emphasizing the experience of using high-performance liquid chromatography – tandem mass spectrometry (HPLC-MS/MS), which allows detecting even very low...

ea0081ep1177 | Late Breaking | ECE2022

Prolonged oral glucose tolerance test in the diagnosis of postprandial non-diabetic hypoglycemia

Yukina Marina , Nuralieva Nurana , Troshina Ekaterina

Introduction: tests alternative to the fasting test are necessary for the diagnosis of numerous causes of non-diabetic hypoglycaemia (NDH), that not provoked by starvation (postprandial hypoglycemia), such as insulin autoimmune syndrome (IAS) and noninsulinoma pancreatogenous hypoglycemia syndrome (NIPHS). However, there is no consensus on the most optimal test (prolonged oral glucose tolerance test (pOGTT) or mixed meal test (MMT)) in this cohort of patients.<p class="abs...

ea0090ep1116 | Late Breaking | ECE2023

Nondiabetic hypoglycemia: the role of psycho-neurological care in primary diagnosis

Yukina Marina , Nuralieva Nurana , Troshina Ekaterina

Introduction: Decreased glycemia in patients without diabetes mellitus (nondiabetic hypoglycemias; NDH) is a manifestation of severe diseases from endocrinopathies to malignant tumors. The most specific symptom of NDH is association of attack with the intake of carbohydrate-containing food. Hypoglycemia is usually manifested by neurological and mental disorders, and therefore, patients initially seek medical help not from an endocrinologist, but from psychiatrists and neurolog...

ea0067o25 | Oral Presentations | EYES2019

Evaluation of microRNA in patients with obesity: association with coronary artery disease

Shvangiradze Teona A , Bondarenko Irina Z , Troshina Ekatreina A

Introduction: Recent studies claim that microRNAs (miRNAs) participate in the pathogenesis of coronary artery disease (CAD).Objective: To study miRNA expression in patients with obesity, determine their association with CAD.Methods: MiRNAs were detected in peripheral blood. 66 patients with BMI 30.0–39.9 kg/m2 were divided into 3 groups: 1st – with CAD and T2DM, 2nd – with T2DM and excluded CAD, 3rd –...

ea0063p54 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

Continuous glucose monitoring during the prolonged fast test for the diagnosis of hypoglycemic diseases: primary data analysis

Yukina Marina , Nuralieva Nurana , Troshina Ekaterina

Introduction: To diagnose the hypoglycemic diseases (HD), firstly, proving the hypoglycemia presence is necessary. For this purpose, the prolonged fast test, which can reach 72 h, is performed. In case of late completion this test has a potential risk of hypoglycemic coma. Repeated glycemia control by glucometer brings discomfort to patients and increases the labor costs of medical workers. In this regard, it was relevant to conduct a study on the comparison of continuous gluc...

ea0063p194 | Diabetes, Obesity and Metabolism 1 | ECE2019

Clinical case of insulin autoimmune syndrome

Yukina Marina , Nuralieva Nurana , Troshina Ekaterina

Introduction: Insulin autoimmune syndrome (IAS) is characterized by the development of hypoglycemia due to insulin and insulin autoantibodies (IAA) interaction. The disease has a strong association with certain alleles of HLA gene. In most cases the disease affects predisposed persons who take drugs containing the sulfhydryl groups. The IAA are also noticed in patients with other autoimmune pathology and in patients with multiple myeloma or monoclonal gammopathy. In c...

ea0011p789 | Thyroid | ECE2006

Ultrasound thyroid changes: Moscow population screening results

Troshina EA , Mazurina NV , Galkina NV , Martirosyan IT

Objective of the study: To determine the prevalence of thyroid tissue changes in mild iodine deficiency region.Materials and methods: The 17-th month-lasting study was carried out in Moscow colleges, factories and offices. 1520 people (1403 female, 117 male) median age – 34 years were screened by thyroid ultrasonography with liner probe 7,5 MHz.Results: Thyroid ultrasound disorders have been demonstrated to be high prevalent i...