Searchable abstracts of presentations at key conferences in endocrinology

ea0016p359 | Growth and development | ECE2008

Lipid peroxidation as possible mechanism of apoptosis activation in low birth weight children

Barg Ewa , Gasiorowski Kazimierz , Wikiera Beata , Skoczynska Anna , Turczyn Barbara , Wojcik Elzbieta , Grabowski Marcin

Children born with low birth weight (LBW, below 2500 g) exhibit slower development with deficit of height susceptibility to recurrent infections, especially of respiratory tract and, in adulthood, an increased risk of developing syndrome X. One possible explanation could be an enhanced elimination of cells by apoptosis.The aim of this study was evaluate of mechanism of lipid peroxidation and activity of caspase 3 in children with low birth weight.<p ...

ea0014p267 | (1) | ECE2007

The polymorphism of PPAR and susceptibility to atherosclerosis in children with low birth weight (below 2500 g)

Barg Ewa , Skoczynska Anna , Wikiera Beata , Chacka Dorota , Glab Ewa , Lebioda Arleta , Turczyn Barbara

Children, who are born with low birth weight (less 2500 g) are known to have an increased risk of developing lipid disturbances and atherosclerosis in later live.PPAR alpha activity could play a regulatory role in the pathogenesis of hyperlipidemia and a modulatory role in the control of inflammatory response.The aim of this study was to determine whether the presence of polymorphism in gene of peroxisome proliferators-activated re...

ea0011p567 | Growth and development | ECE2006

Lipid peroxidation, activity of caspase 3 and apoptosis activation in low birth weight children

Barg E , Gasiorowski K , Wikiera B , Skoczynska A , Turczyn B , Glab E

Children born with low birth weight (LBW, below 2500 g) exhibit slower development with deficit of height and, in adulthood, an increased risk of developing syndrome X. One possible explanation could be an enhanced elimination of cells by apoptosis. The aim of this study was evaluate of mechanism of lipid peroxidation and activity of caspase 3 in children with low birth weight.Subjects for study were 10 children with LBW and growth retardation (SDSHV&#60...

ea0016p596 | Paediatric endocrinology | ECE2008

The superoxide dismutase and lipid peroxide in children with Down syndrome and congenital heart disease

Wojcik Elzbieta , Barg Ewa , Gromkowska Malgorzata , Maslowska Ewa , Wikiera Beata , Kalita Danuta , Gamian Elzbieta , Turczyn Barbara , Skoczynska Anna

Metabolic disturbances occur more often in patients with Down Syndrome (DS, trisomy 21) than in the health population.Superoxide dismutase (SOD-1), the main enzyme in the antioxidative system, is coded on chromosome 21. Disturbances in the antioxidative system may play a major role in the development of complications of CHD with arterio-venous shunt.The aim was to evaluate the activity of SOD-1 and concentration of LPO in children ...