Searchable abstracts of presentations at key conferences in endocrinology

ea0024p3 | (1) | BSPED2010

Pseudohypoaldosteronism Type 1 in Infants: A UK Experience

Amin N L , Barth J H , Field H P , Frazer S , Finlay E , Tyerman K , Feather S , Fitzpatrick M , Saville G , Alvi S , Mushtaq T

Background: Type 1 pseudohypoaldosteronism (PHA) is characterised by resistance to aldosterone action, resulting in salt wasting, hyperkalaemia and metabolic acidosis in the neonatal period. Type 1 PHA can be classified as Renal PHA (autosomal dominant (AD)), and the more severe Multiple target organ defect / systemic PHA (autosomal recessive (AR)). The aim of this study was to ascertain the incidence of PHA, and characterise mode of presentation, management and clinical outco...