Endocrine Abstracts

Introduction: Primary Hyperparathyroidism (PHPT) is a frequent endocrine disease which requires surgical excision for definitive cure. Apart from genetic role in its pathogenesis, there are conflicting reports about role of immunomodulation in literature. In this context, we set out study the role of Pro- inflammatory cytokines in PHPT in South Indian population.Material and methods: This prospective case-control study was conducted on surgically managed...

Introduction: Taking a photograph of self alone or with a group called Selfie, has become modern day rage with spurt in smart phone technology. It has catapulted from a hobby in to psychiatric ailment, especially amongst teens and young adults. Though, it is considered as a psychiatric aberration keeping them aloof from social interactions, we observed an inadvertent advantage in this habit. In this context, we present some intriguing findings through this study.<p class="...

Background: Mid-life obesity is a risk factor for Alzheimer’s disease (AD). On the contrary, late-life obesity has been identified as a protective factor for dementia. Recent published studies have shown that weight loss predicts and precedes dementia diagnosis by decades. Thus, paradoxical effect of body weight across lifespan, the so called “obesity paradox”, might be explained by reverse causality. Structural magnetic resonance imaging (MRI) has been extensiv...

Background: Severe congenital growth hormone deficiency (cGHD) is a rare but potentially life-threatening condition. Even though random growth hormone (GH) can confirm cGHD during the first week of life, the diagnosis remains extremely challenging in the absence of reliable reference values in healthy neonates and thus of a best diagnostic cut-off.Aims: First, to provide solid reference values for GH concentrations in term newborns, by means of a non-inv...

Background and Aim: Congenital growth hormone deficiency (cGHD) is a rare but life-threatening condition whose diagnosis is challenging in the absence of reliable reference values, both in healthy neonates and in preterm ones. We recently estimated GH reference interval in 1036 healthy, at-term newborns (HN) form dried blood spot samples using a previously validated analytical method. Aim of this study is to provide values for random GH in preterm newborns (PN).<p class="a...