Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1360 | Thyroid (non-cancer) | ECE2017

Mirela Tirnovan1, Anamaria Bursuc1, Alina Daniela Belceanu1, Adina Manolachie1, Ioana Armasu1, Iulia Crumpei1, Georgiana Constantinescu1, Luminita Apostu2, Carmen Vulpoi1

Tirnovan Mirela , Bursuc Anamaria , Belceanu Alina Daniela , Armasu Ioana , Crumpei Iulia , Manolachie Adina , Apostu Luminita , Vulpoi Carmen

Introduction: Many causes of malabsorbtion of levothyroxine (LT4) in patients with hypothyroidism have been thoroughly described in literature. Pseudomalabsorption, poor compliance of the patient is most common cause of failure of LT4 and/or liothyronine (LT3) treatment.Case report: 27 years old woman, normopondeal, presented from the age of 11 years for short stature. Further investigations found pluritrope pituitary insufficiency ...

ea0032p112 | Calcium and Vitamin D metabolism | ECE2013

Effects of vitamin D fortified bread on muscle strength

Mocanu Veronica , Costan Anca Roxana , Vulpoi Carmen

Background: Vitamin D deficiency is common in elderly nursing home residents. It has been associated with low bone mineral density, muscle weakness, increased body sway and falls. Evidence indicates that supplementation of vitamin D in these individuals helps to improve locomotor function and general health.Patients and methods: We evaluated, in a 12 months interval, the effects of vitamin D supplementation on grip strength in 45 nursing home residents (...

ea0014p395 | (1) | ECE2007

Body fat concentration is a poor predictor of bone mineral content in hyperthyroid women

Vulpoi Carmen , Branisteanu Dumitru , Zbranca Eusebie

Hyperthyroidism has significant impact upon both bone turnover and body composition. The present study was designed to investigate whether there is a connection between changes in body composition and bone mineral content at female patients with perturbed thyroid function. Sixty-seven long standing (over 6 months) overt hyperthyroid women had significantly lower bone mineral content as expressed by the Z score measured by quantitative ultrasonography (−0.86+/−0.69 ...

ea0032p82 | Bone and Osteoporosis | ECE2013

The value of PRP/PRF in the treatment of bisphosphonates-induced maxillary osteonecrosis: preliminary study

Costan Victor-Vlad , Ciofu Mihai Liviu , Popescu Eugenia , Vulpoi Carmen

Background: Intravenous bisphosphonates treatment brings real benefits to patients with bone metastases. Unfortunately, this treatment sometimes has a difficult to treat complication, often disabling for the patients – the osteonecrosis of the jaws. A new approach in the management of this complication is the use of platelet rich plasma (PRP).Patients and methods: Five patients aged between 62 and 72 years old (three men and two women) were included...

ea0037ep111 | Steroids, development and paediatric endocrinology | ECE2015

The beast behind the dwarf

Rimbu Cosmina , Damian Lisandra , Leustean Letitia , Miron Ingrith , Florescu Alexandru , Vulpoi Carmen , Ungureanu Maria Christina

Abnormalities of growth are one of the most common reasons for the paediatric–endocrinology consults. It’s an obvious manifestation with countless possible causes behind, and sometimes we can have unexpected diagnosis.Case presentation: we investigated the case of a 4 years old girl, born at term, naturally, SGA: birth weight=1950 g, who presented in the Endocrinology Department for short stature. Clinical evaluation: 89.5 cm (−4 DS), 11 ...

ea0037ep996 | Thyroid (non-cancer) | ECE2015

Ultrasound-guided fine-needle aspiration biopsy is an efficient diagnostic tool in thyroid nodules

Armasu Ioana , Ciobanu Delia , Istrate Andra , Vasiliu Ioana , Ionescu Lidia , Preda Cristina , Mogos Voichita , Vulpoi Carmen

Introduction: Thyroid nodules are commonly encountered in clinical practice, the main diagnostic problem being the benign or malignant nature of the nodules. Fine-needle aspiration biopsy (FNAB) is a standard diagnostic test for evaluating thyroid nodules. Several studies have showed that the use of ultrasound guidance (US-FNAB) improves the diagnostic accuracy of aspiration biopsies in comparison with palpation guidance (P-FNAB) alone.Patients and metho...

ea0037ep1318 | Clinical Cases–Thyroid/Other | ECE2015

Is thymectomy a solution for myasthenia gravis associated with autoimmune thyroid diseases?

Vasiliu Ioana , Bodescu Ioana , Stefanescu Cipriana , Ciobanu Delia-Gabriela , Ionescu Lidia , Serban Ionela Lacramioara , Vulpoi Carmen

Myasthenia gravis (MG) and autoimmune thyroid diseases (AITD) may coexist and influence one another clinical expression. The opportunity of thymectomy in this association is controversial, since not all the studies have proven its efficacy. We report eight patients (one man and seven women) diagnosed with AITD (Graves’ disease (GD) – five cases, Hashimoto’s thyroiditis (HT) – three cases) and MG. The AITD diagnosis preceded (two cases), followed (three case...

ea0032p88 | Bone and Osteoporosis | ECE2013

Lean body mass and leptin, but not fat mass are independent predictors of bone mass in postmenopausal women

Constantinescu Georgiana , Novac Roxana , Gaspar Ioana , Preda Cristina , Vulpoi Carmen , Mogos Voichita , Branisteanu Dumitru D

Body weight is positively correlated to bone mass. While gravity represents a stimulation stress for bone turnover, endocrine function of adipocytes may also influence bone.Objectives: We investigated the relative influence of weight, body composition and leptin upon lumbar bone mass in pre and postmenopausal women.Materials and methods: Cross-sectional study including six groups varying from 8 to 15 pre- / postmenopausal healthy v...

ea0032p607 | Female reproduction | ECE2013

Main determinants of serum uric acid concentrations in polycystic ovary syndrome patients

Leustean Letitia , Preda Cristina , Ungureanu Maria Christina , Cristea Cristina , Mogos Voichita , Ungureanu Didona , Vulpoi Carmen

Introduction: Uric acid may increase cardiovascular risk, exerting proinflammatory, pro-oxidant and proliferative actions at the endothelial cell level. Classic and non-classic cardiovascular risk markers cluster in women with polycystic ovary syndrome (PCOS), uric acid being proposed as one of them. The studies available at present regarding serum uric acid levels in PCOS patients are scarce and controversial. The aim of the study was to examine the relationship between uric ...

ea0032p903 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Efficacy of hGH treatment in pituitary dwarfism- age does matter

Idriceanu Jeanina , Vasiliu Ioana , Popovici Ramona , Bodescu Ioana , Rusu Cristina , Mogos Voichita , Vulpoi Carmen

Introduction: The spectrum of GH deficiency (GHD) in children ranges from complete deficiency, with severe growth retardation, to partial deficiency, with slightly short stature. The administration of GH to children with GHD improves linear growth, mainly during the first 2 years of treatment.Patients and methods: The study analyzes pattern of growth in 35 children (24 boys, 11 girls) with GHD, in the first year of treatment with hGH. There were three gr...