Endocrine Abstracts

Introduction: Genes involved in common complex disorders such as obesity, type 2 diabetes mellitus (T2DM), dyslipidemia or hypertension are not disease specific, since clinically related disorders also share genetic components. These diseases cluster together in the Metabolic Syndrome, a generalized pathology with increased cardiovascular risk in which insulin resistance is considered a key feature. Cysteine protease Calpain-10 (CAPN10) has been associated with T2DM, polycysti...