Searchable abstracts of presentations at key conferences in endocrinology

ea0011p775 | Thyroid | ECE2006

The effect of high calcium on activity of thyroid gland in rat

Ebrahimian F , Zahedi_Asl S

The effects of goitrogens on the thyroid gland have been much studied and calcium is considered as a goitrogen in some cases. Since the level of calcium is high in drinking water of some cities of Khuzestan province, the effects of high calcium intake on the function of thyroid gland is investigated in this study. For this purpose the concentration of thyroid hormones is measured in rats.The study was carried out on73 male and female rats. The animals we...

ea0010p89 | Thyroid | SFE2005

The effect of high calcium on activity of thyroid gland in rat

Ebrahimian F , Zahedi Asl S

The effects of goitrogens on the thyroid gland have been much studied and calcium is considered as a goitrogen in some cases. Since the level of calcium is high in drinking water of some cities of Khuzestan province, the effects of high calcium intake on the function of thyroid gland is investigated in this study. For this purpose the concentration of thyroid hormones is measured in rats.The study was carried out on73 male and female rats. The animals we...

ea0020p517 | Paediatric Endocrinology | ECE2009

Serum nitric oxide metabolites and clustering of metabolic syndrome components in paediatrics: an exploratory factor analysis

Ghasemi Asghar , Zahedi-Asl Saleh , Azizi Fereidoun

Objective: To determine risk factor pattern of the metabolic syndrome (MetS) and its association with serum nitric oxide metabolites (NOx) in children and adolescents.Subjects and methods: A cross-sectional study was carried out in 409 male and 442 female children and adolescents aged 4 to 19 years. The ethical committee of our institute approved the study. The MetS was defined according to modified ATPIII criteria and factor analysis was used...

ea0020p535 | Growth and Developmental Endocrinology | ECE2009

The effect of fetal hypothyroidism on carbohydrate metabolism during adulthood in rats

Farahani Hamid , Asl Saleh Zahedi , Ghasemi Asghar

Introduction: Thyroid hormones have major effects on regulation of metabolism and function of most cells. A number of prevalent diseases during adulthood have been attributed to the intrauterine status during fetal life. In this study, the effect of fetal hypothyroidism on the carbohydrate metabolism during adulthood investigated.Subject and methods: After mating, the pregnant rats were divided in two, the fetal hypothyroidism (FH) and the control (C) gr...

ea0011p808 | Thyroid | ECE2006

Effect of oral administration of propylthiouracil during pregnancy and lactation period on isolated aorta response of their adult male off springs

Zahedi S , Khaksari M , Shafiee M , Gasemi A

Thyroid Hormones have extensive effects on differentiation, development, and growth of different organs. In this study the effect of the administration of PTU on pregnant and lactating rats on isolated aorta response of their adult offsprings has been investigated. Three groups of female rats were selected. In the first group (fetal group) observation of vaginal plug after mating was considered as the first day of pregnancy, then PTU was added to their drinking water until the...

ea0020p348 | Diabetes and Cardiovascular | ECE2009

Paradoxical effects of GABA on glucose-stimulated insulin secretion from isolated islets in rat

Shahrivar Farzaneh Faraji , Ghasemi Asghar , Motamedi Fereshteh , Asl Saleh Zahedi

Introduction: The islets of pancreas contain relatively high levels of Gamma-amino butyric acid (GABA). This study was designed to determine the role of the GABA and GABAB receptor on glucose-stimulated insulin secretion of isolated islets in rats.Materials and methods: The Collagenase digestion technique was used to isolate the islets from male Wistar rats and insulin secretion was assessed in islets exposed to glucose (8.3, 16.7 mM) in prese...

ea0020p497 | Obesity and Metabolism | ECE2009

Prevalence of hypo- and hypermagnesemia in an urban population

Siadmoradi Leila , Ghasemi Asghar , Zahedi Asl Saleh , Azizi Fereidoun

Background: Magnesium is the fourth most abundant action in the body and plays an important role in metabolic processes. Association between magnesium deficiency and clinical condition including hypertension, diabetes, insulin resistance, hyperlipidemia, and atherosclerosis. Although magnesium deficiency is associated with a variety of medical conditions, the prevalence of hypo- and hypermagnesemia have not been reported in general population.Methods: Th...

ea0020p537 | Growth and Developmental Endocrinology | ECE2009

The effect of gestational hypothyroidism on insulin secretion from isolated islets of adult offspring in male rats

Zahedi-Asl Saleh , Farahani Hamid , Ghasemi Asghar , Faraji Farzaneh , Manaheji Homa

Introduction: Any abnormalities during pregnancy can affect the growth and development of the fetus and may have a long lasting effect presented during adulthood (intrauterine programming). In this study, the effect of maternal hypothyroidism on insulin secretion from the isolated islets of offspring has been investigated in male rats.Materials and methods: In Test group maternal hypothyroidism was induced using 0.02% propylthiouracyl in drinking water t...