Endocrine Abstracts

The Hypothalamic Pituitary Thyroid (HPT) axis is well-known as a classic endocrine negative feedback loop: increased levels of thyroxine (T4) in the blood are associated with a reduction of thyroid stimulating hormone (TSH) production and vice versa. However, the HPT axis is sensitive to alterations by a number of endocrine-disrupting chemicals (EDCs). Exposure to specific EDCs can deregulate the negative feedback loop and alter the TH/TSH levels. The intrinsic mechanisms for ...

Introduction: Mild iodine deficiency in the Faroe Islands raises a concern for pregnant women. Iodine is essential for thyroid hormone synthesis, making it crucial for thyroid function during pregnancy and foetal growth. World Health Organization (WHO) classifies iodine intake in pregnant women as insufficient if the median urinary iodine concentration (UIC) is below 150 µg/l. We investigated how UIC relates to thyroglobulin (Tg) and thyroid-stimulating hormone (TSH) in s...

Background: In the current digital age, social media brought information to our fingertips but also facilitated the spread of misinformation. The exponential growth of short video platforms shows potential for formulating evidence-based techniques to ensure the dissemination of accurate information without bias.Objectives: 1. To create and disseminate peer-reviewed short videos about PCOS and Thyroid conditions. 2. To explore content creators’ exper...

Introduction: A recent study suggests that copeptin, a surrogate measure of the hormone vasopressin and a known risk marker of cardiometabolic disease and decreased hydration, is non-linearly related to outdoor temperature with increased levels in both hot and cold temperatures. The same u-shaped relationship has been suggested between outdoor temperature and other hydration markers. In this study, we investigated the effect of apparent outdoor temperature on plasma sodium, th...

Toxic metals can disrupt the endocrine system, harming the thyroid and male reproductive function, as indicated by epidemiological and experimental studies. A human biomonitoring study in Serbia determined the levels of toxic metals (Cd, Pb, As, Hg, Cr, and Ni) in the blood to identify real life scenario of exposure. On the basis of the metal measured levels, the doses for the oral 90 days treatment of male Wistar rats were calculated. The experiment included a control group a...

Male infertility arises as a global public health in the context of the dramatic decrease in birth rates. However, the underlying causes of male infertility remain unknown in many cases. An increasing number of studies suggest that environmental and behavioral factors (smoking, drinking, etc) may affect the hormone levels and other pathways involved in male fertility. The aim of this study was to investigate the influence of various environmental factors and hormonal profiles ...