Searchable abstracts of presentations at key conferences in endocrinology
Previous issue | Volume 99 | ECE2024

26th European Congress of Endocrinology

Stockholm, Sweden
11 May 2024 - 14 May 2024

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We are pleased to announce that ECE 2024 will be held in Stockholm, Sweden from 11-14 May 2024. We will, once again, be offering the hybrid format next year so you can join us in person in Sweden or remotely with ECE@Home.

Pre-Congress Course

Growth Hormone Research Society (GRS) Congress (Day1)

ea0099pcc2.5 | Growth Hormone Research Society (GRS) Congress (Day1) | ECE2024

Growth hormone, mini-mice, football, dirty shorts, and a new drug

Kopchick John J

The growth hormone receptor antagonist was discovered via expression of mutated GH genes in transgenic mice. Although we were attempting to generate potent GH analogs, our mouse studies indicated that the compound was ‘inhibiting’ GH action. We subsequently showed that it was a GH receptor antagonist, the first of its type. Many hurdles needed to be ‘jumped’ in the development of this compound into a drug including protection of intellectual property; fundi...