Endocrine Abstracts

Intoduction: Diabetic retinopathy remains one of the major causes of blindness. The management of the diabetic patient is multidisciplinary. The objective is to study the prevalence of retinopathy in a group of type 2 diabetic patients and to update the risk factors.Patients and methods: This is a cross-sectional study during 3 years of 129 type 2 diabetic patients followed up for endocrinology and metabolic diseases at the Mohammed VI University Hospita...

Introduction: Cushing’s disease is caused by endogenous hypercotisolism, due to the hypersecretion of the adenocorticotropic hormone (ACTH) by an ACTH-secreting pituitary adenoma. However, some patients with Cushing’s disease have no visible adenoma on MRI. The goal of this study is to review the clinical features, diagnosis and medical preparation of patients with Cushing’s disease.Material and Methods: A retrospective study including ...

Introduction: Cushing’s syndrome is a rare condition, resulting from chronic exposure to excessive circulating levels of glucocorticoids. This condition is highly associated with complications such as cardiovascular and metabolic disorders. This study aims to review the clinical characteristics, diagnosis and treatment of patients with ACTH-dependent Cushing’s syndrome.Material and Methods: A descriptive and comparative study carried out in t...

Introduction: Acromegaly is a quite rare and insidious disease caused by the oversecretion of growth hormone and subsequently insulin - like growth factor 1. Recent studies have demonstrated an increased co-existence of different thyroid lesions with acromegaly. However the data concerning this co-occurrence remains a matter of debate. The purpose of this study is to shed light on the different thyroid lesions concerning the patients with acromegaly who are followed up in the ...

Introduction: Pheochromocytoma is a rare tumor. It can be revealed or complicated by cardiovascular manifestations. The aim of our work is to study the cardiovascular manifestations of pheochromocytoma and the evolution of hypertension after surgery.Patients and methods: A retrospective study of 18 cases of pheochromocytoma followed at the endocrinology and metabolic diseases department of Mohammed VI university hospital of Oujda during a period of 5 yea...

Introduction: Musculoskeletal manifestations of endocrine disorders are a heterogeneous group of disease, often giving rise to various clinical or radiological individuals. Osteoporosis is a not uncommon complication of endocrine disease. It may even be accompanied by endocrinopathy.Aim of study: Determine mineral bone density profile of patients with endocrinopathy and define the characteristics of osteoporosis and osteopenia in these patients.<p cl...

Objective: Diabetic ketosis is very often a reason for emergency consultation in diabetics. The objective of our study was to assess the etiologies of ketotic decompensations in diabetics.Methods: It was a descriptive cross-sectional study of 80 diabetics hospitalized at the National Institute of Nutrition for ketotic decompensation. Each patient underwent a clinical examination with a standard biological assessment.Results: The av...

Introduction: Darier disease, also known as dyskeratosis follicularis, is a rare autosomal dominant genodermatosis characterized by a persistent eruption of keratotic papules. It is caused by mutations in the ATP2A2 gene encoding sarcoendoplasmic reticulum Ca 2+ -ATPase isoform 2 in the endoplasmic reticulum. Since it is expressed in most tissues, other organs besides the skin may be involved in Darier disease. In this case, we report a patient treated for Darier disease who w...

Introduction: Diabetes in the elderly is often accompanied by other comorbidities, particularly dyslipidemia, which considerably increases the cardiovascular risk in these patients.The aim of our work was to determine the lipid profile in elderly diabetic subjects.Methods: This was a descriptive and analytical study carried out on 100 elderly type 2 diabetics hospitalized in our department for unbalanced diabetes. Each patient unde...

Introduction: Insulin therapy ( IT) in type 2 diabetes( T2D) is an integral Pharmacologic Approache because of the progressive nature of the disease. Insulin improves glycemic control and reduces the risk of microvascular complications. It’s however associated with weight gain as a side effect which promotes insulinoresistance and cardiovascular morbi–mortality.In this work we evaluated long–term weight gain in insulin–treated pat...