Endocrine Abstracts

Background: Polycystic ovarian syndrome (PCO) is the most common endocrinopathy in adult women, and is emerging as a common cause of menstrual disturbance in the adolescent population. Insulin resistance, which is considered one of its underlying causes, has increased substantially in the past decade, putting more adolescent girls at risk for PCOS and its complications. Anti – Mullerian hormone (AMH) is secreted by the granulose...

Background: Mortality and morbidity after acute myocardial infarction (AMI) remain high even when myocardial reperfusion is successful. Thus, additional approaches are warranted. Erythropoietin (EPO) was found to be a cytoprotective molecule that might represent a novel strategy to limit the infarct size.Aim of the work: To investigate serum erythropoietin level and its relation to infarct size in Egyptian patients with AMI.Methods...

Introduction: Occult carcinoma of the thyroid is defined as a microcancer less than 1 cm in size, clinically undetectable. Discovered accidentally during routine radiological examination, cervical surgery of a benign thyroid tumor, varies from 0.01% to 35.6%. Mostly it is papillary type. Occult cancers revealed by bone metastasis have rarely been reported. We report two patient observations presenting bone localizations of occult thyroid carcinoma.Observ...

Polycystic ovary syndrome is the most common endocrine disorder of reproductive women. This syndrome is often associated with cardiovascular risk.Objective: Our objective was to assess the prevalence of cardiovascular factor in len PCOS women.Materials and methods: Sixty-eight lean PCOS were prospectively evaluated for glucose intolerance, dyslipidémie and high blood pressure from 2004 to 2007.Results: I...

Introduction: Prolactinoma are the most frequent pituitary adenoma, considered benign tumor and well respond to medical treatment, but sometimes, in men prolactinoma may be invasive and aggressive occurring neurological signs.Case 1: Male 53 years old, went to ophtalmology consulting for progressive vision problems associated with headaches from more than a year but denied. On examination visual field showed poor vision in left eye and temporal defect on...

Introduction: Medullary thyroid cancer (MTC) accounts for 5-10% of thyroid cancers.25% of cases may be hereditary related to multiple endocrine neoplasia type 2 A (MEN2A) and associated with pheochromocytoma. Metastases from CMT are preferentially lymph node chains. However, other localizations are possible such as adrenal metastases which remain exceptional.Observation: We report the case of a 35-year-old patient with CMT for which he underwent thyroide...

Introduction: The association between Graves’ disease and thymic hyperplasia was first described in 1912. Hundreds of cases have since been described. This rare association doesn’t seem fortuitous. We report a case.Observation: A 30-year-old patient with no particular personal history who consults following the onset of dyspnea with chest tightness. A CT scan of the chest revealed thymic hyperplasia. The preoperative assessment found an hyperth...

Introduction: Azoospermia is identified in approximately 1% of all men and in 10 to 15% of infertile males. A precise diagnosis of azoospermia and systematic evaluation of the patient to establish the disease etiology are needed to guide appropriate management options. The development of intracytoplasmic sperm injection (ICSI) as an efficient therapy for severe male factor infertility has become an appropriate treatment for the majority of male reproductive tract deficiencies....

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder and is frequently associated with insulin resistance and type 2 diabetes mellitus. At present, women with type 1 diabetes mellitus (T1DM) are being treated with supraphysiological doses of exogenous insulin with the aim of providing a strict metabolic control. The prevalence of PCOS in women with T1DM varies depending on the diagnostic criteria employed and on the ethnicity of the population s...

Introduction: The sellar plasmacytoma, an exceptional localization that can be solitary or associated with a multiple myeloma. We report the case of a sellar mass wrongly diagnosed as an invasive non-functional pituitary adenoma, the diagnosis was rectified postoperatively by the anatomopathological study.Case description: A 44 year old female patient, with history of cholecystectomy and megaloblastic anemia, was referred to our center for management of ...