Endocrine Abstracts

Background: Plasma carnitine insufficiency has been caused muscle weakness. Carnitine levels and pulmonary functions were lower in patients with diabetes.Objective: To determine whether pulmonary functions are correlated with carnitine levels in patients with type 2 diabetes.Setting: Internal medicine outpatient clinic of a university hospital.Methods: Forty-nine patients with type 2 diabetes and 34 healthy c...

BackgroundObesity is an increasing public health problem all around the world. It plays role in the pathogenesis of many diseases, especially diabetes, hypertension, hyperlipidemia, cardiovascular diseases and cancer. The prevalence of weight-loss surgery is increasing as a result of developments of surgical techniques. In parallel with these developments, more patients admit for weight-loss surgery. Pharmacotherapy is one of the most important component...

Introduction: Although the thyroid isthmus seems like a structure that connects bilateral lobes, it is an undiscovered area that needs to be explored. Currently, the data is evolving that the increase in the risk of malignancy is higher in the isthmic nodules, and extrathyroidal extensions and lymph node metastases are more common in isthmic-derived malignant thyroid nodules. Therefore, we aimed to compare the malignancy rate of isthmic and lobar nodules, the ultrasonographic ...

Introduction: 80–90% of insulinomas are smaller than 2 cm, equally located in the head, body and tail of pancreas. Computer tomography (CT) is 75%, magnetic resonance imaging (MRI) is 55–90%, endoscopic ultrasonography (EUS) is 85–95% and selective arterial calcium stimulation test (SACST) is 95–100% sensitive in the diagnosis of insulinomas. Here, we presented two cases of insulinoma which could not be located by conventional methods and evaluated with SAC...

Thyroid nodules have 3–7% freuquency in general population. FNA biopsy is an important diagnostic tool for patients with thyroid nodules. There are many reporting systems for FNA biopsy and Bethesda system is the most common one. The aim of this retrospective study, detect the atypia of undetermined significance (AUS) rates in the patients who performed FNA biopsy and evaluate the concomittant biopsy results of this patients and malignancy rates in the patients who were c...

Context: Polycystic ovary syndrome (PCOS) is a common and complex endocrine disorder. Emerging animal and human data point out to various changes in microbiota that could be linked with the syndrome. However, the effects of therapeutic approaches on gut microbial composition in women with PCOS remain unknown.Objective: We aimed to assess whether gut microbial composition is altered in overweight/obese women with PCOS and to determine potential impact of ...

Primary hyperparathyroidism (PHPT) is usually caused by single adenoma. Functional parathyroid cysts are a rare cause of PHPT. Parathyroid cysts can be subdivided into nonfunctional, without biochemical derangement, or functional, with elevated serum calcium accompanying clinical evidence of hyperparathyroidism. Parathyroid cysts are found in the neck and anterior mediastinum. Functional parathyroid cysts are not only secretary but larger cysts can lead to compression symptoms...

BackgroundMedullary thyroid carcinoma (MTC) accounts for 3–5% of thyroid cancers, but recurrent MTC, manifested by elevated calcitonin levels, is a common problem. We aimed to perform a calcitonin washout procedure simultaneously with cytological evaluation and compare their effectiveness to diagnose metastatic lymph nodes.Methods94 patients diagnosed with MTC were recruited from our institutional datab...

Background: Adrenal venous sampling (AVS) is the gold standard diagnostic approach for differentiating unilateral from bilateral primary aldosteronism (PA). However, it is a costly, invasive, and operator-dependent procedure with restricted availability.Objectives: It was aimed to develop a prediction model based on a simple clinical score with prominent parameters from the current literature for the subtype diagnosis of PA. The contribution of adrenal v...

IntroductionExtramedullary hematopoiesis (EMH) refers to hematopoiesis occurring outside the bone marrow. Pathologic EMH can be caused by thalassemias or disorders in the hematopoietic system. Sites of EMH can be widespread however, most common localizations are in the spleen, liver, and lymph nodeCase reportA 22-year-old male patient was referred to the endocrinology department for bilateral adrenal masses f...