Endocrine Abstracts

Background: 55 year-old male is admitted in 2019 to the hospital for relapsed MEN syndrome.Case report: The pacient first presented to the hospital in march 2012 acusing dysphonia. He was diagnosed with vocal cord paralysis due to locoregional extension of MTC, based on the ultrasound aspect, calcitonin >2000 pg/mL, chromogranin=123 ng/mL and also with primary hyperparathyroidism due to right lower parathyroid adenoma (hypercalcemia=12.8 mg/dl, PTH=2...

Affecting multiple aspects of every-day living, Covid-19 could be a stress-promoting event, and short-stature patients could be an at-risk population. The scope of our study is to assess whether the on-going pandemic could affect children’s response to growth hormone therapy. This was a retrospective study that evaluated children on growth hormone treatment who presented for clinical visits between September 2019 and January 2021 at the Pediatric Endocrinology Department ...

Introduction: Hyponatremia, defined as a serum sodium concentration below 135 mEq/l, has a heterogeneous etiology, the main endocrine causes includind the syndrome of inappropiate antidiuresis (SIAD), adrenal insufficiency and severe hypothyroidism.Materials and methods: Clinical, hormonal and imaging evaluationAim: To present a case of hyponatremia leading to the diagnosis of a large pituitary tumorCase pres...

Introduction: Intrasellar arachnoid cysts are rare and clinically resemble nonfunctional pituitary adenomas. Arachnoid cysts should be considered in the differential diagnosis of cysts developing in the sellar region, together with cystic pituitary adenoma, craniopharyngioma, epidermoid cysts, and Rathke’s cleft cysts. Symptomatic cysts are operated but can recurr.Case presentation: We present 2 cases of compressive intrasellar arachnoid cysts occur...

Beta-thalssaemia major (BTM) is a rare disease that encompasses a vast range of endocrinological complications, despite of the improvement of treatment protocols. The aim of this study was to identify the clinical and hematological parameters associated with osteoporosis, a frequent complication found in beta-thalassaemia patients.Patients with BTM were evaluated in the Endocrinology Department of Elias Hospital between February 2004 and March 2016. Only...

Objective: The occurrence of cardiovascular disease (CVD) in patients suffering from type 2 diabetes is a widely discussed issue, less so in those with type 1 (T1DM). The purpose of this study was to evaluate the frequency of these complications as well as certain risk factors that they are associated with.Material and methods: We conducted a retrospective observational study by analyzing data from the observation charts of 106 patients evaluated in our ...

Objective: Diabetic foot complications are a main cause for hospital admissions and spending for patients suffering from T1DM or T2DM. The purpose of this study was to identify and compare possible risk factors for patients suffering from such issues.Methods: We conducted a retrospective observational study analyzing data from observation charts of 324 patients, diagnosed with T1DM or T2DM as well as various foot issues, evaluated between January 2015 &#...

Background: Association of differentiated thyroid carcinoma (DTC) and cortisol-producing adrenal adenoma is not part of the classical MEN syndromes. We present a clinical case raising the question of a common etiology for these tumours.Case Presentation: A 58-year-old female presented in 2010 for the investigation of a 6 cm left adrenal tumour incidentally discovered by abdominal CT. Medical history included smoking, obesity, myocardial infarction, hyper...

Congenital adrenal hyperplasia (CAH) is a group of diseases which develop as a result of deficient enzymes or co-factor proteins required for cortisol biosynthesis. Depending on the defect, the manifestations range from life-threatening salt-wasting syndrome to almost no symptoms. Nevertheless, some subclinical subtypes can cause impediments in particular situations. This case brings to light a possible manifestation of CAH, revealed in the process of in-vitro fertilization. W...

Introduction: Premature pubarche is defined as early appearance of pubic or axillary hair without any other signs of puberty, before 8 years of age in girls and 9 years in boys. We present the case of a 6 months old boy who came to us with scrotal hair since birth with moderate progression until present.Case presentation: A 6 months old male patient was referred to our clinic to investigate the presence of thick scrotal hair, affirmatively present at bir...