Endocrine Abstracts

Objective: Diabetic foot complications are a main cause for hospital admissions and spending for patients suffering from T1DM or T2DM. The purpose of this study was to identify and compare possible risk factors for patients suffering from such issues.

Methods: We conducted a retrospective observational study analyzing data from observation charts of 324 patients, diagnosed with T1DM or T2DM as well as various foot issues, evaluated between January 2015 – December 2017 in our clinic. The patients were divided into 2 groups: T1DM and T2DM (40 and 284 patients – 25% female and 75% male, respectively 23% and 77%).

Results: The T1DM group was younger (P = 0.0000012642), leaner (P = 0.0000000043), had been diagnosed at a younger age (P = 0.00...01), had a longer duration of disease (P = 0.0000200919), more hospital admissions (1.97 vs 1.41, P = 0.015709446), poorer glycemic control (9.69 vs 8.60%, P = 0.000124519), but better TG and HDL-cholesterol levels (137.20 vs 165.99 and 47.65 vs 39.82 mg/dl, P = 0.030880937, P = 0.003798103). Statistically significant differences between patients with amputations and those only with soft tissue damage for the T2DM group: sex (P = 0.022714), kidney impairment (P = 0.01 989), retinopathy (P = 0.01 0754), mean no. of days/hospital admission (8.06 vs 7.26 days, P = 0.029889513), BMI (29.35 vs 30.64 kg/m², P = 0.04805204), glycemic control (8.38 vs 8.86%, P = 0.040931604), HDL-cholesterol levels (38.73 vs 41.05 mg/dl, P = 0.04 601). For the T1DM group: kidney impairment (P = 0.003782032), mean no. of days/hospital admission (9.06 vs 6.12 days, P = 0.0000191641), total and LDL – cholesterol (161.19 vs 188.15 and 88.25 vs 109.35 mg/dl, P = 0.019094005, P = 0.013594543).

Conclusions: Identifying risk factors should help in establishing prevention measures for diabetic foot issues.