Endocrine Abstracts

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a cancer syndrome characterized by the development of neuroendocrine tumors of the pituitary gland, parathyroid and pancreas, and other neoplasms such as adrenocortical tumors and carcinoid.Observation: We report the case of a 70-year-old women with acromegaly that diagnosed 15 years ago, in relation with pituitary macroadenoma (30×25 mm) invading the left cavernous sinus and in contact wit...

Cowden’s syndrome (CS), also called multiple hamartoma syndrome is an orphan pathology which associates pathognomonic cutaneous-mucosal manifestations with multiple and disseminated hamartomas (skin, mucous membranes, gastrointestinal tract, thyroid, breasts and genitourinary system) and an increased risk of the development of certain malignant tumors, in particular breast, thyroid and endometrial tumors, which are very serious.Observation<p cla...

Hyperthyroidism is a clinical situation characterized by an excess of thyroid hormones in the circulation, the most common etiology of which is Graves’ disease. Its treatment is based on ATS, iodine 131 and surgery. The iratherapy, object of our study, is a treatment of current practice. It is a simple and radical treatment whose goal is to switch to euthyroidism or hypothyroidism. In case of failure or recurrence, a 2nd or even a 3rd cure is prescribed. We conducted a re...

Introduction: Obesity is a risk factor for cardiovascular disease and diabetes. The objective of this work is to study the prevalence of obesity among a consultant population at the Hygiene Service of the Sidi-Othman District (ASO) in Casablanca.Patients and methods: This is a case-control study of subjects consulting the Sidi Othmane hygiene service. Socio demographic, anthropometric data (weight, height, waist circumference, hip circumference, body mas...

Introduction: Blood groups and the Rh factor are involved in several pathologies. Some studies have also identified them as risk factors for diabetes. The objective of this work is to evaluate the possible association between ABO blood groups, rhesus (Positive, Negative) and the risk of diabetes.Patients and methods: This is a case-control study involving 257 diabetic patients followed in the hygiene department and 266 controls followed at Sidi Othmane H...

Introduction: Sheehan’s syndrome is a rare postpartum complication. Recurrent hypoglycaemia,though described is a rare complication of Sheehan syndrome. Here we report a case of Sheehan syndrome which presented with hypoglycemic coma.Case Presentation: We report the case of a 47-year-old woman who presented to the medical emergency unit with coma. There was no history of chest pain, fever, headache, vomiting, trauma, or seizures. She had no history ...

Background: Hyponatremia is common in hospitalized patients and its differential diagnosis and management challenging. An important mechanism is suppressed or adequately or inadequately secreted plasma arginine vasopressin (AVP). Therefore, plasma vasopressin levels may help in the differential diagnosis and in therapy management. Copeptin is secreted in an equimolar ratio to AVP and is more reliable to measure.Methods: In this prospective observational ...

Papillary thyroid carcinoma is rare in young patients and have a good prognosis, although it is often diagnosed at the stage of lung metastases. Our multicenter study included 15 children aged between 5 and 18 years with female predominance, followed for differentiated thyroid cancer with lung metastases. All these patients underwent a whole body scan with I-131, serum thyroglobulin, chest radiography and/or cervico-thoracic CT. Scintigraphy had shown pulmonary miliary among a...

Introduction: Thyroid tuberculosis is a rare disease, its frequency is 0.15–0.2% of autopsic data. We report a case of micro papillary carcinoma of thyroid revealed by thyroid tuberculosis.Observation: Mrs. K.J aged 54 years presented a multinodular goiter without ultrasound signs of malignancy. The patient underwent total thyroidectomy. Histological examination revealed a granulomatous and giganto cellular inflammation which is in favor of a tuberc...

Introduction: Cardiovascular complications are well known in type 2 diabetes with other factors of cardiovascular disease. Recently, with the intensive treatment of type 1 diabetes, many studies have focused on macrovascular complications in type 1 diabetes. The aim of our study was to determine the long-term cardiovascular risk factors and macrovascular complications in type 1 diabetic patients.Patients and methods: A retrospective study involving 45 pa...