Endocrine Abstracts

Background: Arterial hypertension (AH) and 2 type diabetes mellitus (2TDM) are the critical risk factors for the development of cardiovascular diseases. Catestatin (CTS) is known as a marker of AH via its antiadrenergic and vasodilating actions, but also can improve insulin sensitivity.Objective: To investigate the relations between CTS levels and parameters of carbohydrate metabolism in patients with AH, including AH with 2TDM, and establish the prognos...

Background: Arterial hypertension (AH) and type 2 diabetes mellitus (T2DM) are common non-infectious diseases with a high tendency to co-exist. Catestatin (CTS) and relaxin-2 have antihypertensive, cardioprotective and metabolic effects and can be considered as biomarkers of these diseases.Objective: To evaluate plasma CTS and RLN-2 levels in hypertensive patients and to investigate their associations with parameters of glucose metabolism and their predi...

COVID-19 significantly influenced global mortality; it caused 6.6 million cases of death. Mortality or crude death rate (CDR) is a typical statistical value for analyzing the demographic processes among the population. In Ukraine, we observed an increase in CDR in 2020-2021. It could be caused directly by the COVID-19 pandemic and indirectly; due to social distancing. Some people avoid visiting a doctor and neglect their treatment of chronic diseases. Comorbidities such as obe...

39-year old female reported usage of methylprednisolone (20–80 mg daily) for three months since the last decade of January 2020. She received methylprednisolone for controlling of panniculitis of Weber-Kristen (diagnosis was proved twice histologically in Ukraine and Austria. Before starting steroid therapy, there was no glucose impairment in her history. The patient has different complaints, including fatigue, increased body temperature, hypersensitivity of the skin, vo...

Introduction: Hyperaldosteronism is not so common in middle-aged groups. But it should be concerned in the case of unclear hypertension, fatigue, or dyspepsia.A 61-year-old female was hospitalized in the private clinic ‘Oberig’ in December 2019. She had non-specific complaints such as weakness, dyspepsia, constipation, vomiting, losing an appetite, decrease in body weight. She has been treated for a long time out-patiently and had some episod...

Diabetes mellitus is a global social and medical problem. In the world, there are 463 million diabetic patients, and in 2045 it is expected to be 700 million (IDF DIABETES ATLAS, Ninth edition 2019). In Ukraine, diabetes affects 7.6% of the Ukrainian population, which is 2.5 million people. According to changes in the public health system, we have separate registration of people with diabetes who receive insulin, but it does not include all diabetic patients. Previous years we...

Introduction: Health promotion of decreasing weight, giving up smoking, and regular physical activity could be helpful in the improvement of individual health.Materials and methods: We analysed the attitude of obesity and high risks for severe COVID-19 for doctors involved in diagnosing and treating such patients in 2020-2022.Results: We asked to admit what type of facility the correspondents represented. We found that 48,4% worked...

The ability of thyroid cell to accumulate iodine is due to presence of sodium iodide symporter (NIS). Differentiated thyroid cancer (DTC) maintain ability to express NIS and thus it makes possible to perform RAI treatment. In case of DTC cells loss the ability of NIS protein production and cell membrane embedding that leads to RAI treatment fail.The aim of our study was to find a relationship between the level of preoperatively defined NIS and recurrence...

Introduction: T2DM prevalence in Belarus is 3.489.5 per 100 thousand people, annual growth rate is 5–6%. STEPS study: in 2016–2017 the following risk factors prevailed: overweight and obesity (61.2%), dyslipidemia (36%), hypertension (50%); inactive lifestyle (78.2%). The study aim was to assess risk factors for metabolic disorders in a young healthy population. Objective. 253 people were examined: 22.1% of men and 77.9% of women under 40. Methods: We performed ant...

Tumour necrosis factor-α (TNF-α) impairs liver function and contributes to the pathogenesis of nonalcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (DM-2) with different trophological status.Purpose: To assess the relationship between the level of TNF-α and indices of carbohydrate metabolism in patients with NAFLD and its combination with DM-2 with different trophological status.Methods:...