Endocrine Abstracts

Introduction: Testosterone circulates in the blood mainly bound to albumin and human sex-hormone-binding globulin (hSHBG). It is generally admitted that only the protein unbound fraction of testosterone (free hormone hypothesis) is biologically active. From our routine SHBG binding assay, we observed that SHBG concentration may have an influence on its affinity for testosterone (personal data). To further explore this assumption we used surface plasmon resonance (SPR, Biacore)...

Background: Pituitary metastasis are rare, however, not well-documented. They are usually encountered in elderly patients with disseminated malignant disease. The most frequent are metastases of breast and lung cancer. We herein report a case of an old patient with pituitary metastasis of a mediastinal lymphoma.Case report: A 88-year-old man with a history of treated prostate cancer and primary hypothyroidism presented to our emergency department with he...