Endocrine Abstracts

Background: Mid-life obesity is a risk factor for Alzheimer’s disease (AD). On the contrary, late-life obesity has been identified as a protective factor for dementia. Recent published studies have shown that weight loss predicts and precedes dementia diagnosis by decades. Thus, paradoxical effect of body weight across lifespan, the so called “obesity paradox”, might be explained by reverse causality. Structural magnetic resonance imaging (MRI) has been extensiv...

Objective: Assessment of the health status in a population from a territory with apparently normal iodine intake may take in consideration the incidence of goiter as a mass pathologic process. Considering goiter as a result of both endogenous and exogenous factors, the study of its incidence and correlations with potentially goitrogens represents a prophylactic medical activity. Use of the term ‘paraendemic’ for a certain territory does not justify a ‘relaxation...

Introduction: Involvement of growth hormone in the maturation and function of the ovary is proved by a series of clinical observations.Scope: Assessing serum levels of IGF1 as a marker of GH activity correlated to age of onset of menarche and menopause.Method: The study groups consisted of 41 patients (group 1) with GH deficiency diagnosed before the age of 8 years and a group of 18 adult patients with pituitary dwarfism who had ea...

This article discusses the assessment of quality of life, psychological state and anxiety-depressive disorders in patients with metabolic syndrome. It is known that the prevalence of metabolic syndrome in different countries is about 30% and varies from included criteria. The problem of the quality of life of obese and overweight patients is relevant and socially significant. Research Methods The authors present the results of a study of 70 patients with MS and 36 apparently h...

Objectives: Hyperthyroidism in pregnancy presents a challenge for medical doctor, patient and products of conception.Aim of the study: To specify the peculiarities of expression of hyperthyroidism in pregnant women, diagnosis, monitoring, treatment, prognosis of pregnancy and effect on the fetus.Materials and methods: The study included a total of 27 women with hyperthyroidism of which 15 (group A) had thyrotoxicosis before concept...

Metabolic syndrome (MS) is a widespread clinical syndrome, the incidence of which is increasing annually in both developing and developed countries. The prevalence of MS among the working population is quite high (20-25%) and tends to increase. The presence of MS increases the risk of developing type II diabetes and cardiovascular diseases, and anxiety and depression are considered as independent risk factors for the development of MS. It has also been found that the prevalenc...

Metabolic syndrome (MS) is a pressing problem of modern medicine. The prevalence of MS has a worldwide tendency to increase and depends on many factors, which explains the difficulty in diagnosis, prevention programs and treatment of this pathology. It has been established that MS has a multifactorial etiology, in which psycho-social factors, genetic and environmental factors are important. At the subclinical stage, functional and biochemical changes associated with MS are rev...

Introduction: Metabolic syndrome (MS) is a common disease with up to 25% of the total adult population and more than 45% of those over 60 years of age. When MS develops a complex of metabolic disorders that contribute to the development of vascular atherosclerotic diseases, such as abdominal obesity, hypertension, insulin resistance, dyslipidemia. Exchange disorders in MS are associated with the development of inflammation in organs and vessels, while the role of neutrophils i...

Aims: Presence of antinuclear antibodies (ANA) is correlated to tissue involutive lesions by microvascular alterations. The possible involvement of hypovitaminosis D as a negative immunomodulatory factor along with the presence of ANA and the incidence of chronic autoimmune thyroiditis (CAT) atrophic form is a complex mechanism with multiple pathological intercorrelations.Material and method: Inclusion criteria: patients - new cases diagnosed with CAT wi...

Objectives: Evaluation of functional thyroid alterations in correlation with hyperemesis gravidarum (HG).Material and method: Study performed on a group of 136 pregnant women with HG and a control group of 101 pregnant women. In both groups, cases with a known history of thyroid disease, molar pregnancy, multiple pregnancies or other systemic chronic diseases were excluded. Patients were clinically and serologically examined (TSH, FT4, ATPO, TRAb), the r...