Endocrine Abstracts

Cadmium (Cd) is a ubiquitously present toxic metal with an established ability to induce endocrine disruption, in literature often referred to as metalloestrogen. Some of the major uncertainties connected with endocrine disrupting chemicals (EDCs) in general, are low-dose exposure and the presence of nonmonotonic dose-response curves. This study aims to elucidate the presence of a dose-response relationship between the measured Cd levels in the tissue (internal dose) and estro...

Toxic metals can disrupt the endocrine system, harming the thyroid and male reproductive function, as indicated by epidemiological and experimental studies. A human biomonitoring study in Serbia determined the levels of toxic metals (Cd, Pb, As, Hg, Cr, and Ni) in the blood to identify real life scenario of exposure. On the basis of the metal measured levels, the doses for the oral 90 days treatment of male Wistar rats were calculated. The experiment included a control group a...

Pseudomonas aeruginosa mannose-sensitive-hemagglutinin (PA-MSHA) is a bacteria-mediated cancer therapy showing promise in inhibiting cancer growth by impeding tumor cells and inducing natural cell death. Clinical studies indicate its ability to enhance chemotherapy efficacy and stimulate the immune system against cancer, presenting manageable side effects such as fever and skin irritation. Nevertheless, the safety profile of PA-MSHA requires further exploration, emphasizing th...