Endocrine Abstracts

Cardiovascular (CV) diseases are the main cause of death in patients with diabetes mellitus. The different phenotypes can predispose to those disease in people with diabetes.Aim: to identify phenotypic features in patients with type 2 diabetes mellitus (T2DM) and their impact on the development of myocardial infarction (MI).Materials and methods: We examined 231 patients with T2DM with and without MI. The average age of patients wa...

Introduction: Cardiovascular autonomic neuropathy (CAN) is a significant risk factor for cardiovascular morbidity, mortality in patients with diabetes mellitus (DM). On the other hand, oxidative stress is one of the important factor of pathogenesis of diabetic complications. However, an association between CAN, cardiovascular autonomic reflex tests (CARTs), heart rate variability (HRV) and markers of oxidative stress in patients with DM was not fully investigated.<p class=...

BackgroundCardiovascular autonomic neuropathy (CAN) is a chronic complication associated with high risk of cardiovascular morbidity and mortality either in patients with diabetes mellitus and prediabetes. However, risk factors of CAN in patients with prediabetes and coronary artery disease (CAD) was not fully investigated.AimsThe aim of this study was to investigate risk factors of CAN in patients with predia...

Background: &Acy;growing body of evidence suggests that type 2 diabetes mellitus (T2DM) may contribute to the the development and deterioration of heart failure (HF) with either reduced or preserved ejection fraction. On the other hand, diabetic kidney disease (DKD) is associated with a high risk and wors&iecy; outcomes of HF. However, the relationship between DKD and various types of HF hasn’t been fully investigated. The aim of this study was to assess the association b...

Background: Chronic kidney disease develops in approximately 40% of patients with type 2 diabetes mellitus (T2DM) and significantly increases the risk of mortality and cardiovascular morbidity. Finerenone, a novel nonsteroidal mineralocorticoid receptor antagonist, has demonstrated a significant impact on renal function by reducing proteinuria and preserving glomerular filtration rate in patients with chronic kidney disease. However, the influence of finerenone on kidney funct...