Endocrine Abstracts

Background: Decidualization, a crucial process for successful pregnancy establishment and maintenance, involves endometrial stromal cell differentiation. This process is orchestrated by estradiol (E2), progesterone, and other stimuli that increase intracellular cyclic adenosine monophosphate (cAMP) levels. The progesterone receptor (PR) plays a pivotal role in regulating decidualization, and alterations in its expression are linked to endometrial pathologies. However, the mech...