ea0037ep157 | Reproduction, endocrine disruptors and signalling | ECE2015
Reyes Aldo
, Ramirez Luisa
, Ambrosetti Valery
, Guerra Marcelo
, Alvarez Daniela
, Olguin Sofia
, Fernandois Daniela
, Sotomayor-Zarate Ramon
, Cruz Gonzalo
Obesity during gestation has been related to predisposition to endocrine and metabolic diseases in the offspring. Regarding reproductive effects, an increase in BMI in pregnant mothers is associated with precocious puberty in their offspring. This has been replicated in animal models of high fat diet (HFD) administration to mothers. Also, gestational obesity has been associated to higher susceptibility to developing breast cancer in the offspring. As both precocious puberty an...