Endocrine Abstracts

Aim: To identify the causes and predictors of mortality in acromegaly patients diagnosed, treated, and followed in the Pituitary Center of Istanbul University-Cerrahpasa over the last three decades using machine learning (ML) models.Methods: The study sample consisted of 607 consecutive patients diagnosed with acromegaly at Cerrahpasa Faculty of Medicine during the period 1990 – 2023. The main inclusion criteria were age > 18 years and a clear-c...

Aim: To investigate the relationship between serum growth hormone (GH) and insulin-like growth factor-1 (IGF-1) levels, seminal plasma GH and IGF-1 levels, and sperm parameters in acromegalic patients.Methods: A cross-sectional study was conducted on 24 acromegaly patients (acromegaly group), 11 non-functioning adenoma (NFA) patients (NFA group), and 16 healthy men (control group). Seminal plasma GH and IGF-1 levels were measured. Semen parameters and se...

Purpose: Patients with acromegaly may have changes in balance due to visual disturbances, musculoskeletal abnormalities and changes in body composition. We aim to compare static and dynamic balances in patients with acromegaly and healthy controls and to evaluate effects of exercise on balance in patients with acromegaly.Methods: Twenty-two patients with acromegaly followed at the Endocrinology Outpatient Clinic of Istanbul University, Cerrahpasa Medical...

Purpose: The authors review the clinical outcomes of patients with hypophysitis.Methods: Medical records of hypophysitis patients who were followed between 2007 and 2018 at Cerrahpasa Medical Faculty were evaluated retrospectively. Clinical, endocrinological, pathological and radiological findings and therapies were assessed.Results: Twenty patients (F/M:12/8) were identified with a mean age at diagnosis of 39.14±17.78 years. ...

Background/Aim: In literature, many previous studies adressed that Gender-affirmig Hormone Therapy (GAHT) improves the factors affecting social functioning such as self-esteem, mental well-being, behavioral health and quality of life. In this study, we aimed to quantitatively evaluate the effects of the GAHT on social functioning using a psychiatric scale in people with female-to-male (FtM) in Türkiye.Methods: The single center, cross-sectional stud...

Transphobia is expressed as negative attitudes, emotions and actions towards transgender individuals or transsexualism. The aim of this study is to investigate the existence of transphobic approaches towards transgender individuals in physicians in different clinics that play an active role in the gender transition process. It was planned to include physicians from the disciplines of psychiatry, endocrinology, gynecology, urology and plastic surgery. A questionnaire was sent t...

Purpose: To evaluate the relationship between basal dehydroepiandrosterone-sulfate (DHEA-S) levels and other tests used in the diagnosis and differential diagnosis of Cushing’s Syndrome (CS) among the patients with pathologically confirmed CS.Methods: In this multicenter study, the data of 623 patients with CS were evaluated retrospectively. The patients were classified as Group 1 (n = 353 Cushing’s disease;CD), Group 2 (n</e...