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Endocrine Abstracts (2023) 90 EP908 | DOI: 10.1530/endoabs.90.EP908

1Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Division of Endocrinology and Metabolism, Department of Internal Medicine, Turkey; 2Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Department of Psychiatry, Turkey


Background/Aim: In literature, many previous studies adressed that Gender-affirmig Hormone Therapy (GAHT) improves the factors affecting social functioning such as self-esteem, mental well-being, behavioral health and quality of life. In this study, we aimed to quantitatively evaluate the effects of the GAHT on social functioning using a psychiatric scale in people with female-to-male (FtM) in Türkiye.

Methods: The single center, cross-sectional study included 77 people with FtM Gender Dysphoria (GD) who were followed-up with for GAT at the Psychiatry or Endocrinology, Metabolism and Diabetes outpatient clinics, between January and April 2022. The sociodemographic data form and Social Functioning Scale (SFS) were used. Informed consent was obtained from all individual participants included in the study. Statistical analyses were performed using the Statistical Package for the Social Sciences (SPSS) software (version 21.0).

Results: We examined a total of 77 people with FtM; 41 had received GAHT and 36 had not received GAHT with a mean age of 24.7 ± 4.5 years. In people with FtM who received GAHT, 75.6% had received hormone therapy under the supervision of a doctor and the median duration of the hormone therapy was 12 (IQR = 5-36) months. When the SFS scores are evaluated from the point of GAHT, people with FtM who received hormone therapy had more social functioning than those who did not, with regard to the SFS total (P= 0.01), social engagement/withdrawal (P= 0.001), interpersonal behavior (P= 0.002) and pro-social activities (P= 0.027) subscales scores. On the other hand, people with FtM who undergone bilateral mastectomy had higher scale scores that predicted more social functioning than those had not. Finally, the SFS total (r= 0.272, P= 0.017), pro-social activities (r= 0.239, P= 0.036) and recreation (r= 0.236, P= 0.039) subscales scores were positively correlated with real-life experience in people with FtM.

Conclusions: The findings of our study indicate that people with FtM GD receiving GAHT and/or undergoing bilateral mastectomy have a significantly increased social functioning. As expected, it can be said that the real-life experience is effective on social functioning in these people.

Volume 90

25th European Congress of Endocrinology

Istanbul, Turkey
13 May 2023 - 16 May 2023

European Society of Endocrinology 

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