Endocrine Abstracts

Introduction: Follicular or vesicular cancers represent 5 to 10% of differentiated thyroid cancers (CTD) and are therefore the second leading cause of endocrine tumors after papillary thyroid cancer. They can be minimally or massively invasive, and thus represent a more aggressive histological type compared to the papillary. The aim of our work is to describe in our context the clinical and evolutionary features of thyroid tumors of vesicular origin.Mate...

Introduction: Neurofibromatosis type 1 (NF1) is the most common autosomal dominant disease. The endocrine manifestations of NF1 are represented by pubertal abnormalities and pheochromocytoma. We report a case.Observation: Mr. G.A, age 28, consulling for a grade 2 HTA evolving for 3 years. The anamnesis notes paroxysmal crises made of Ménard triad. The exam notes a correct blood pressure, 18 coffee latte tasks, lentiginous tasks. Two neurofibromas of...

Introduction: Acromegaly is a rare endocrinopathy, potentially fatal by its metabolic, cardiovascular and neoplastic impact. The aim of this work is to study the cardiovascular impact of acromegaly and cardiovascular risk factors during acromegaly.Materials: This is a retrospective, descriptive study of 43 acromegalic patients admitted to the Department of Endocrinology, Diabetology and Metabolic Diseases CHU IBN ROCHD, Casablanca from January 2005 to De...

Background and aims: It has been demonstrated that the thyroid autoimmunity, during pregnancy, adversely affects the course of the pregnancy. The anomalies may be prior to the conception, hence the interest of studying the women during the genital activity period. Our objective was to determine the prevalence of the thyroiditis in childbearing age women.Materials and methods: Prospective study, on 270 childbearing age women. Study protocol: clinical exam...

Background and aims: The hypothyroidism may be prior to the conception, hence the interest of studying women during the genital activity period. Our objective was to determine the prevalence and the etiologies of the hypothyroidism in childbearing age women.Materials and methods: Prospective study, on 270 childbearing age women. Study protocol: clinical examination, urinary iodine, thyroid stimulating hormone (TSH), free thyroxine (FT4) and thyroid antib...

Background: Hyperprolactinaemia is common in patients presenting with polycystic ovary syndrome (PCOS). Recent studies suggest that each condition has an independent aetiology, hence appropriate investigation of hyperprolactinaemia in the context of PCOS is required, for which separate treatment may then be provided. Appropriate investigation includes a serum macroprolactin screen, a specific drug history for drug-induced hyperprolactinaemia (DIH), blood tests to exclude secon...

Objective: To highlight the issue of vitamin D supplementation in patients with sarcoidosis.Case report: We report the case of a 66-year-old lady, who presented with one week history of general weakness, drowsiness, nausea and confusion. 6-weeks prior to presentation, she underwent right-sided intra-medullary nail insertion for a traumatic femur fracture, whilst abroad. Her past medical history includes stage IV pulmonary sarcoidosis, pulmonary hypertens...

Neonatal immune hyperthyroidism is a rare but potentially fatal condition. It occurs in 1–5% of infants born to women with Graves’ disease (GD). We present a case of neonatal thyrotoxicosis due to maternal hypothyroidism secondary to radioactive iodine treatment for Graves’ disease. A new-born female at 13-days of age was readmitted due to maternal concerns. She noted the baby to be jittery, unsettled, tachycardic and tachypnoeic. The infant was born via a spont...

Xerostomia can be classified into two different types. One type is associated with severely reduced salivary secretion. The other involves normal salivary function yet reduced viscosity of saliva or reduced mucin concentration within the saliva, a common finding in elderly people. Studies show that xerostomia is the most common oral side-effect of cardiovascular medication. Statins are common cardiovascular drugs used to treat hypercholesterolemia. A 55-year-old Asian lady, no...

Introduction: Iodine deficiency has serious consequences for both the mother and the offspring, it is a real public health problem. Our aim was to study the iodine status impact on thyroid parameters during the first trimester of pregnancy in women free of any current or previous thyroid disease.Patients and methods: Prospective study, on 145 pregnant women (mean age of 29.4±0.5 years) at 10.4±0.2 weeks of gestation. Women with disrupted thyroi...