Endocrine Abstracts

Our previous study showed that polycystic ovary syndrome (PCOS)-like reproductive and metabolic phenotypes induced by maternal dihydrotestosterone (DHT)-exposure, can be passed on in mice from mothers (F0) to daughters (F1), granddaughters (F2), and even to great-granddaughters (F3). The female transmission is independent of diet-induced obesity and is mediated by transcriptional and mitochondrial perturbations of oocytes accompany. ...

Introduction: Rathke Cleft Cysts(RCCs) are benign cysts arising from the remnants of Rathke’s pouch. The most common symptoms are visual field disorders, headache, and pituitary dysfunction. Case 1: A 26-year-old male was admitted with headache that started 4 days ago. Cranial MRI revealed an appearance mimicking a hemorrhagic adenoma in pituitary. Pituitary hormones were found as normally. Pituitary MRI showed a 12x10x10 mm hemorrhagic RCCs located...

Introduction: Rathke Cleft Cysts(RCCs) are benign cysts arising from the remnants of Rathke’s pouch. The most common symptoms are visual field disorders, headache, and pituitary dysfunction. Case 1: A 26-year-old male was admitted with headache that started 4 days ago. Cranial MRI revealed an appearance mimicking a hemorrhagic adenoma in pituitary. Pituitary hormones were found as normally. Pituitary MRI showed a 12 x 10 x 10 mm hemorrhagic RCCs loc...

Introduction: Primary thyroid lymphoma is a rare malignancy. In many series, it is reported that it is seen at a rate of 0.6-5% among thyroid cancers and approximately 2% among extranodal lymphomas. It is often seen as a painless mass in the neck. Almost all of them have underlying Hashimoto’s thyroiditis. In many instances, thyroid lymphoma was recognized after thyroid surgery for suspected carcinoma. The most common thyroid lymphomas are B-cell and Hodgkin lymphomas. Th...

Objective: Hereditary pituitary adenomas (PAs) are rare and occur either isolated or as part of a syndrome. Familial isolated pituitary adenoma (FIPA) is the presence of only PA in at least two members of a family, where “Aryl hydrocarbon receptor interacting protein-AIP” gene mutations have been identified in 10-20% of cases. However, the cause of tumorigenesis in the majority is unknown. We aimed to identify novel genetic variants in a cohort of FIPA patie...

Background: William-Beuren region duplication syndrome (WBDS) is a rare multisystem disease caused by the gain on chromosome 7q and transmitted autosomal dominant, with approximately a population frequency of 1 in 13,000-20,000. The age of diagnosis is variable, but generally, it is diagnosed during childhood. It include endocrine (growth hormone deficiency) and non-endocrine (facial dysmorphology, cardiovascular problems, gastrointestinal and genitourinary problems, neurologi...

Introduction: Hashimoto’s thyroiditis (HT) is caused by a variety of genes, cytokines, receptors, and environmental factors. A series of enzymes known as type 1 and type 2 deiodinases (D1, D2) are in charge of converting thyroxine (T4) into triiodothyronine (T3). It is believed that the low free T3 (fT3) levels caused by D2 polymorphism may result in thyroid autoimmunity through the induction of inflammation. However, iodothyronine deiodinase (DIO) gene polymorphism and H...

Aim: The aim of this study was to determine the malignant potential of thyroid nodules with macrocalcifications and to evaluate the role of other sonographic findings in the diagnosis of malignancy in thyroid nodules besides macrocalcifications.Method: The findings of 8250 patients who applied to our outpatient clinic and underwent thyroid ultrasonography(US) between 2008 and 2021 were retrospectively reviewed. We included a total of 303 patients with 30...

Purpose: The coronavirus disease 2019 (COVID-19) has a high morbidity and mortality in patients with chronic disorders. This study was aimed at assessing the frequency and outcomes of COVID-19 in patients with lipodystrophy syndrome and investigating the effect of restricted access to the hospital during pandemic on metabolic parameters.Methods: A survey comprising descriptive questions about the situation of the patients during the COVID-19 pandemic was...

Lymphocytic infundibuloneurohypophysitis (LINH) is rarely reported due to lymphocyte infiltration in the neurohypophysis. Causes of central diabetes insipidus include idiopathic diabetes insipidus (DI), primary or secondary tumors or infiltrative diseases (such as Langerhans cell histiocytosis, lymphocytic hypophysitis), neurosurgery and trauma.Case: A 59-year-old female patient presented with complaints of fatigue for 1 month, dry mouth and drinking a l...