Endocrine Abstracts

Introduction: A retrospective study of the year 2003, of 1314 women with GDM, was performed.Patients and methods: Two groups according to pre-pregnancy BMI: Go - BMI&gE;30 Kg/m2; Gno BMI<30 Kg/m2. Mean age 32.9±5 years, A1c<6% in both groups. Influence of BMI in different variables was analysed: family history of DM, weight gain during pregnancy; blood pressure, need of insulin, gestation age at the beginning of insulin...

IntroductionHearing loss may be associated with autoimmune diseases, but it was less studied in Hashimoto’s thyroiditis (HT). We aimed to evaluate hearing impairment by audiometric assessments in adults with euthyroid HT.Materials and MethodsAdult patients with euthyroid HT (normal thyroid functions, positive AntiTPO/AntiTg and sonographic findings) were compared with controls. We excluded pregnant or ol...

IntroductionThe malignancy risk of an adrenal nodule is based on clinical symptoms (rapid onset of hypercortisolism and hyperandrogenism; mass symptoms) and imaging characteristics. These suspicious criteria include boundary irregularities, heterogeneity, dimension>6 cm and density>20 HU (CT). However, these are not absolute criteria.Case reportWe report the case of a 43 years-old female patient with a histor...

Aldosterone and cortisol coproducing adrenal adenoma is a rare type of primary aldosterone. Previous reports mostly describe single adrenocortical adenomas that simultaneously secrete aldosterone and cortisol. To date, only 7 cases of bilateral adrenocortical adenomas with independent functions of secreting different hormones have been reported in the published English literature. Here, we study an extremely rare case of a left adrenocortical adenoma secreting aldosterone and ...

Introduction: Hypophysitis is a rare condition characterized by inflamation of the pituitary gland, causing mass effect and hypopituitarism. The incidence is estimated to be 1in9 million/year. The diagnosis of hypophysitis is based on clinical and laboratory findings, imaging methods and histopathology in selected cases. The aim of the treatment is to eliminate the compression effects of the mass and to treat hypopituitarsim. The first choice in medical treatment is immunsupre...

Introduction: While Graves’ disease is a common cause of thyrotoxicosis, tyroid hormone resistance (THR) is a rare cause of high thyroid hormones. Coexistence of Graves’ disease and THR which can cause quite a lot of difficulties in diagnosis and treatment was reported very rarely in the literature. Here, we report a patient with THR and Graves’ disease in whom remission was achieved with medical therapy.Case: A 38-year-old woman applied t...

Introductıon: Rathke’s cleft cysts (RCCs) are benign lesions originating from the epithelial remnants of Rathke’s pouch with a peak incidence at 30–50 years of age. It is detected at a rate of 13–33% in several autopsy series. RCC is usually asymptomatic and diagnosed incidentally. In symptomatic cases, common symptoms are headache, visual disturbance, and symptoms related to hypopituitarism.Case: A 28-year-old male patient prese...

Type 1 diabetes mellitus (T1DM) not only is congenital disease that known as insulin-dependent diabetes, often occurs in children and adolescents. Recent advances in quantitative proteomics including fluorescence two-dimensional differential gel electrophoresis (2D-DIGE) and matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) have offered opportunities to discover plasma proteins as biomarkers for tracking the progression and for underst...

Objective: Gonadotroph adenomas are the most common subtype of pituitary adenomas. Rarely, clinical findings may occur due to the secretion of high amounts of biologically active gonadotropins. It may affect platelet activity if there is an excessive increase in the release of estrogen and testosterone or if it is used in pharmacological doses. In this study, we aimed to investigate whether platelet activity indices and coagulation parameters were affected in silent gonadotrop...

Crooke cell corticotroph adenomas are a rare subtype of corticotroph adenomas. It can be detected in less than 1% of all pituitary adenomas. They are usually noticed as invasive macroadenomas on preoperative imaging. They are expected to have a more aggressive course and more frequent recurrences during their clinical course. We present a case series of 11 patients who were followed up with Cushing’s Disease in our clinic and were diagnosed with Crooke cell adenoma after ...