BES2002 Poster Presentations Clinical Case Reports (60 abstracts)
A case report of hungry bone syndrome in the course of Graves disease
SN Boysan , P Kadioglu , O Tiryakioglu , O Acbay & S Gundogdu
Division of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul,Turkey.
We report a case of hungry bone syndrome occured as thyrotoxicosis treated in the patient of Graves disease.
The patient was a 37 year-old woman resistant to antithyroid therapy. Radioactive iodine ablation was applied as 10 milicuri. After the serum levels of thyroid hormones decreased to the normal range spontaneous tetany occured.Serum ionised calcium was 4.18 miligram per decilitre(4.25-5.24) and serum phosphate was 2.3 miligram per decilitre(2.5-4.5). Osteocalcine measured as bone formation marker was in the upper range: 42.2 nanogram per mililitre(12-41). N-telopeptides in the urine measured as bone resorption marker increased: 235 nanomole per milimole creatinine(16-56). The parenteral treatment of hypocalcemia needed .Also we started vitamin D active preparation and elemental calcium per oral.High doses of vitamin D and elemental calcium need to correct hypocalcemic presentation.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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