ea0009p28 | Diabetes and metabolism | BES2005
, Digby J
, Chen J
, Randeva H
The adrenal gland is implicated in energy homeostasis, and dysfunction of this gland contributes to a variety of metabolic disorders including the development of hypertension, diabetes, osteoporosis, and obesity. Recently, adipokines have been implicated in adrenal function. Adiponectin, an adipokine, with insulin sensitising and anti-inflammatory properties, exerts its effects by activating two distinct seven transmembrane domain receptors, adiponectin-R1 (adipoR1) and -R2 (a...