Searchable abstracts of presentations at key conferences in endocrinology
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196th Meeting of the Society for Endocrinology and Society for Endocrinology joint Endocrinology and Diabetes Day

Poster Presentations

Endocrine tumours and neoplasia

ea0010p38 | Endocrine tumours and neoplasia | SFE2005

Pre operative localization of 28 consecutive parathyroid adenomas. A prospective imaging/surgical outcome correlation study

Kitchener P , Leelarathna L , Greenwood R , Heyburn P , Colin J , Pain S

IntroductionThere is general consensus that parathyroid excision is the treatment of choice for primary hyperparathyroidism. Minimally invasive surgery with limited neck exploration has the benefits of reduced operative and recovery times, less complications and excellent cosmetic results. However the success of unilateral neck exploration depends on the accurate preoperative localization of a parathyroid adenoma.Objective<p cl...

ea0010p39 | Endocrine tumours and neoplasia | SFE2005

Bilateral laparoscopic adrenalectomy offers good palliation for medullary thyroid cancer associated with ectopic acth secretion

Hyer S , Haq M , Harmer C

We present three cases of metastatic medullary thyroid carcinoma who developed severe CushingÂ’s syndrome from ectopic production of ACTH by the tumour. Following total thyroidectomy and external beam radiotherapy, the patients had remained symptom-free for 4, 9 and 25 years after initial presentation despite the presence of widespread hepatic metastases. However, with the onset of CushingÂ’s syndrome, patients became unwell with severe muscle weakness and lethargy. Me...

ea0010p40 | Endocrine tumours and neoplasia | SFE2005

The RET mutation E768D confers a late onset FMTC-only phenotype with incomplete penetrance

McCall D , Dabir T , Russell C , Morrison P , Hunter S

Mutations of the RET proto-oncogene are associated with MEN and FMTC and aid diagnosis and predictive testing in family members. Genotype-phenotype correlations are also used to plan therapeutic decisions. We describe a 4 generation family with a rare E768D mutation in exon 13. The index case was diagnosed with MTC at age 54 and remains free of clinical disease 11 years following thyroidectomy and neck irradiation. 2 further family members were identified with MTC at age 25 an...

ea0010p41 | Endocrine tumours and neoplasia | SFE2005

An audit on hypercalcaemia. Tools of the trade

Arefin A , White C

Introduction: Primary hyperparathyroidism (PHP) is common; Prevalence and Incidence are now much higher than the past. There is also a change in practice related to medical management, surveillance, and defining criteria for diagnosis as well as the recommendation for surgery.Decision to send patients for surgery was considered primarily on their calcium level.Other criteria for surgery were largely ignored.E...

ea0010p42 | Endocrine tumours and neoplasia | SFE2005

Octreotide in the treatment of pthrp related hypercalcaemia in neuroendocrine tumours: a case report and literature review

Jones R , OaGrady J , Chambers S , Heaton N , Ramage J , Aylwin S

Intro: A subset of pancreatic and gastric neuroendocrine tumours (NET) are associated with hypercalcaemia attributed to tumour secretion of parathyroid hormone related peptide (PTHrP). Hypercalcaemia may be severe and refractory to conventional treatment....