Searchable abstracts of presentations at key conferences in endocrinology
Previous issue | Volume 11 | ECE2006 | Next issue

8th European Congress of Endocrinology incorporating the British Endocrine Societies


Green over-the-counter endocrinology

ea0011s75 | Green over-the-counter endocrinology | ECE2006

Regulation of steroid receptor expression and proliferation in prostate cancer by genistein and other flavonoids

Bektic J , Guggenberger R , Schäfer G , Bartsch G , Klocker H

A diet rich in phytoestrogens such as flavonoids has been attributed as one of the reasons for the low incidence of prostate cancer in Asia as opposed to Western countries with a diet rich in fat and meat and the highest incidences of this cancer. In many cellular models of prostate cancer these substances, the prototype of which is genistein, inhibit cell proliferation and cell cycle progression and enhance the rate of apoptosis. The molecular mechanisms involve modulation of...

ea0011s76 | Green over-the-counter endocrinology | ECE2006

Soy, flavonoids and osteoporosis

Lydeking-Olsen E

Osteoporosis and the associated low- energy fractures is a major public health problem. Phytoestrogens, especially from soy foods with isoflavones, carry the potential of being a nutritional candidate for prevention of osteoporosis. Several studies have been performed to determine the role of soy intake in preventing bone loss in postmenopausal women. Studies with fracture endpoint are not yet available, but several other lines of evidence have been investigated: epidemiologic...

ea0011s77 | Green over-the-counter endocrinology | ECE2006

Aftermath of WHI: the risks or benefits of red clover and soy extracts in postmenopausal OTC HRT

Wuttke W

Soy and red clover extracts contain high concentrations of isoflavones, particularly of genistein, which bind to both estrogen receptors α and ß (ERα and ERß). Lifelong nutrition rich in soy proteins or soy protein isolates appear to exert positive effects on certain health aspects including the development of mammary cancer but the beneficial effects become questionable when soy/isoflavone-rich nutrition starts in later adult life. Stimulatory effects on m...