Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2006) 11 P282

ECE2006 Poster Presentations Diabetes, metabolism and cardiovascular (174 abstracts)

The metabolic syndroma presence in peripheral arterial occlusive disease of diabetic patients

DS Tesic , P Pantelinac , M Mitrovic , R Pejin , J Radosavljevic , D Naglic , D Tomic & I Obrovacki

Clinic for Endocrinology, Diabetes and Metabolic Diseases, Novi Sad, Zimbabwe.

Background and Aims: The aim of our investigation was to evaluate the relationship between parameters of the metabolic syndroma (MSDR; NCEP/ATPIII Panel) in randomly selected diabetic patients (DM) with peripheral arterial occlusive disease (PAOD).

Materials and Methods: diabetics, male 680 (49.7%), age (mean+SD) 52.6+14.4yrs. (16–84), were propectively examined using doppler examination and neuropathy disability scoring (NDS). PAOD was confirmed in 67 T2DM pts. (4.8%; G1 group) while mediosclerosis in 10 (0.73%; G2 group).

Results: Age difference (t test) was found between G1 and G3 (control) groups (62.5±8.3 yrs. vs. 64.2±5.9 yrs, P<0.05). Age of G2 group was 56.5±13.7 yrs\. VPT was significantly lower in both G1 and G2 groups in relation to G3 (5.1±2.6 vs. 3.2±2.9 vs. 6.7±1.7; P<0.001). Significantly higher ankle reflexes score was present in G1 comparing with G3 group (3.3±1.3 vs. 2.4±1.6; P<0.001). MSDR was present in 51pts. (76.1%; contingency tables, Chi sq., P<0.001) with 3 components in 38.8%, 4 in 23.9% and 5 in 13.4%pts\. In the 16 (23.9%) nonMSDR pts., 8 (11.9%) had cholesterol >6.5 mmol/l, and 7 (10.4%) were smoker. In G1 group high BP was in 48pts. (71.6%; P<0.001), hyperTG in 52pts. (77.7%; P<0.001). Multiple regression analysis with Winsor’s index as dependent variable showed following significant constelations: TG, HDL and W (P0.06); TG, HDL, W and cigarette number (p 0.02); cholesterolemia and cigarette number (P<0.001).

Conclusions: T2DM patients with PAOD have a significant presence of MSDR. The fact that MSRD, hyperCHOL and current smoking covers almost all PAOD cases should increase awareness of a PAOD as the part of cardiovascular health.

Volume 11

8th European Congress of Endocrinology incorporating the British Endocrine Societies

European Society of Endocrinology 
British Endocrine Societies 

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