The possible role of inhibin in the etiology of polycystic ovary syndrome (PCOS) is controversial. This study was designed to investigate levels of serum inhibin in women with PCOS.
In a case-control setting 41 women with PCOS and 44 women with normal cycles (control group) aged 1540 year-old were evaluated. Mean age of cases and controls was 23.6±5.3 and 23.1±3.9 years, respectively. Mean body mass index (BMI) in cases and controls were 25.07±5.45 and 21.3±3 2.46 Kg/m2, respectively. There was no statistically significant difference in mean age between the two groups (P>0.05) but mean BMI was significantly different between the two groups (P<0.001). Mean serum levels of inhibin in cases and controls were 1.62±1.23 and 2.26±2.26 U/ml, respectively which was not significantly different between the two groups (P: 0.16).
We concluded that basal inhibin levels cannot be used for routine screening in women with PCOS.
01 - 05 Apr 2006
European Society of Endocrinology