Searchable abstracts of presentations at key conferences in endocrinology
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197th Meeting of the Society for Endocrinology

ea0012p1 | Bone | SFE2006

Primary hyperparathyroidism – a great masquerader

Muthukrishnan J , Verma A , Jagdish Kumar P , Patro K , Modi KD , Jha S , Jha R

Primary Hyperparathyroidism is known to present with protean manifestations leading to misdiagnosis in the initial stages of the disease. In the developing world, most of the cases are detected late when they manifest with severe symptomatic metabolic bone disease or renal stones. Distal Renal Tubular Acidosis is a rare complication of primary hyperparathyroidism and should be looked for, in cases presenting with nephrolithiasis. Nuclear scintigraphy accurately localizes the t...

ea0012p2 | Bone | SFE2006

The effect of bisphosphonates on calcium and parathyroid hormone levels in patients with primary hyperparathyroidism over 2 years

Knight MJ , Hyatt PJ

IntroductionPrimary Hyperparathyroidism (PHPT) has a prevalence of 1/1000, with only 20% of patients being symptomatic, and was previously considered to be a benign condition. Recent evidence shows increased mortality in PHPT patients, primarily from cardiovascular disease, peptic ulcers and osteoporotic fractures. Parathyroidectomy reduces mortality in PHPT patients. High parathyroid hormone (PTH) levels may increase mortality independently of raised ca...

ea0012p3 | Bone | SFE2006

Growth hormone stimulates osteogenesis activity of alveolar bone derived-osteoblasts from adolescents

Crippa Grasiele Edilaine , Beloti Marcio Mateus , Rosa Adalberto Luiz

The major role of GH during adolescence is to promote longitudinal bone growth, but GH continues to have important metabolic actions throughout life. Additionally, there are evidences of its hole in the maintenance of adult bone mass by regulating bone remodeling during adulthood. However, while GH therapy increase density mineral bone in childhood and adolescent, its effects in adults bone are not clear. The aim of this study was to investigate the effect of GH in human osteo...

ea0012p4 | Bone | SFE2006

Audit on the efficacy of intravenous Pamidronate in the treatment of osteoporosis

Arefin AN , Orme SM

IntroductionOsteoporosis is a common disease characterised by a decrease in bone mass attributed to an imbalance between bone formation and resorption. Oral bisphosphonates have proven efficacy in increasing bone mineral density (BMD) and fracture reduction. Prior to the introduction of i.v. Ibandronate, patients who were unable to tolerate oral bisphosphonate were treated with i.v. Pamidronate (APD).AimTo as...