Endocrine Abstracts

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The polycystic ovary syndrome (PCOS) is actually considered not only a reproductive disease but also a multifaceted disease with metabolic, cardiovascular and long-term health implications, including diabetes mellitus and coronary artery disease. In particular, insulin resistance, hyperandrogenemia and dyslipidemia are likely the major risk factors for the occurrence of cardiovascular disease (CVD) in PCOS. These cardiovascular risk (CVR) factors are often evident at an early ...

Marked secular trends in obesity prevalence are apparent throughout childhood, and this is leading to more adolescent girls presenting with clinical features of PCOS, including acne, hirsutism and menstrual irregularity. These girls typically also have central obesity and relatively early menarche (onset of first menstrual period).Certain overweight and obese girls may be particularly prone to developing PCOS features. Several studies have identified a r...