Endocrine Abstracts

Epigenetic mechanisms provide a potential explanation for how environmental influences in early life cause long-term changes in chronic disease susceptibility. Whereas epigenetic dysregulation is increasingly implicated in human developmental syndromes and cancer, the role of epigenetics in complex chronic diseases such as cardiovascular disease, type 2 diabetes and obesity remains largely uncharacterized. The inherent tissue-specificity of epigenetic regulation is the foremos...