Endocrine Abstracts (2009) 20 P339

Change of physical activity, diet habits and risk of diabetes after lifestyle intervention. Diabetes in Europe: prevention using lifestyle, physical activity, and nutritional intervention: the DePlan Project Krakow

Aleksandra Gilis-Januszewska1, Alicja Hubalewska-Dydejczyk1, Beata Piwonska-Solska1, Zbigniew Szybinski1, Jaana Linstrom2, Marku Peltonen3, Peter Schwarz1, Noel Barengo2 & Jaakko Tuomilehto2

1Chair and Department of Endocrinology, Collegium Medicum, Jagiellonian University, Krakow, Poland; 2Department of Public Health, University of Helsinki, Helsinki, Finland; 3Diabetes Unit, Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland; 4Department of Medicine III, Medical Faculty Carl Gustav Carus of the Technical University Dresden, Dresden, Germany.

Aim: Aim of the study was to assess the effectiveness of the structured lifestyle intervention in diabetes type 2 high risk people.

Methods: The De-Plan Project participants were selected based on FINDRISK over 14. Exclusion criteria were known or OGTT diabetes. Intervention completed by 175 participants consisted of 10 group sessions on lifestyle changes, diet and physical activity education, and 6 telephone motivation sessions and voluntary physical activity sessions 1–2 a week. Fasting and OGTT blood glucose, blood pressure, fasting lipids, weight, dietary and physical activity habits were assessed twice, before and after one year of intervention.

Results: Fasting and after OGTT glicaemia lowered in 38.9 and 51.4% participants. Fasting cholesterol, HDL and triglicerydes lowered in 53.7, 44.6 and 50.3% of intervened respectively. SBP and DBP decreased in 26.9 and 33.7% participants. Weight was lowered in 63.4% of study participants, 24.6% participants lost more than 5% of initial body weight (P<0.05). Changes in physical activity and nutritional patterns are given in the Table below.

AllWeight loss≥5%
Physical activity increased during last year7.4*25.7*4.7*39.5*
Diminished total amount of fat in diet25.1*52.6*20.9*65.1*
Changed fat to unsaturated29.1*61.7*37.2*72.1*
Increased consumption of fruits and vegetables24.0*51.4*30.2*53.5*

After the intervention FINDRISK diminished in all study participants from 18.31 to 15.95 (P<0.05) and in those with weight loss ≥5% from 18.23 to 16.29 (P<0.05).

Conclusions: Intervention on lifestyle changes, diet and physical activity education is possible and may produce diminished risk of type 2 diabetes.