Aim: Aim of the study was to assess the effectiveness of the structured lifestyle intervention in diabetes type 2 high risk people.
Methods: The De-Plan Project participants were selected based on FINDRISK over 14. Exclusion criteria were known or OGTT diabetes. Intervention completed by 175 participants consisted of 10 group sessions on lifestyle changes, diet and physical activity education, and 6 telephone motivation sessions and voluntary physical activity sessions 12 a week. Fasting and OGTT blood glucose, blood pressure, fasting lipids, weight, dietary and physical activity habits were assessed twice, before and after one year of intervention.
Results: Fasting and after OGTT glicaemia lowered in 38.9 and 51.4% participants. Fasting cholesterol, HDL and triglicerydes lowered in 53.7, 44.6 and 50.3% of intervened respectively. SBP and DBP decreased in 26.9 and 33.7% participants. Weight was lowered in 63.4% of study participants, 24.6% participants lost more than 5% of initial body weight (P<0.05). Changes in physical activity and nutritional patterns are given in the Table below.
|Physical activity increased during last year||7.4*||25.7*||4.7*||39.5*|
|Diminished total amount of fat in diet||25.1*||52.6*||20.9*||65.1*|
|Changed fat to unsaturated||29.1*||61.7*||37.2*||72.1*|
|Increased consumption of fruits and vegetables||24.0*||51.4*||30.2*||53.5*|
After the intervention FINDRISK diminished in all study participants from 18.31 to 15.95 (P<0.05) and in those with weight loss ≥5% from 18.23 to 16.29 (P<0.05).
Conclusions: Intervention on lifestyle changes, diet and physical activity education is possible and may produce diminished risk of type 2 diabetes.
25 - 29 Apr 2009
European Society of Endocrinology