Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2010) 22 P336

ECE2010 Poster Presentations Diabetes (103 abstracts)

Therapeutic objectives in the care of patients with diabetes mellitus type 2 in clinical practice at an endocrine department

Carmen Tenorio Jiménez 1 , Pablo Jose Lopez Ibarra 2 , Manuel Romero Muñoz 2 & Maria Jimenez del Valle 2


1Hospital General de Ciudad Real, Ciudad Real, Spain; 2Hospital Clinico San Cecilio, Granada, Spain.


According to the American Diabetes Association (ADA), achieving specific treatment goals in type 2 diabetes can substantially reduce microvascular complications, including retinopathy, nephropathy and neuropathy. Intensive management has also been shown to have a beneficial effect on cardiovascular disease. The objective of the study is to evaluate the degree of achievement of appropriate target levels for A1C, as an index of chronic glycaemia, LDL-c and blood pressure, in a large and homogeneous sample of type 2 diabetes patients, evaluated periodically in an endocrine service. The study reviewed the clinical and biochemical data of 200 adults with type 2 diabetes, diagnosed using ADA criteria and followed by a specific diabetes unit. The primary endpoints were HBA1c ≤7%, blood pressure (BP) ≤130/80 mmHg and LDL-c ≤100 mg/dl. It was also collected measures of body mass index (kg/m2) and waist (cm) and reports about additional medical treatments: the use of statins, lowering pressure medications and insulin therapy.

The mean age of the 200 patients was 61.1±10.2 years of which 53% were female. The mean duration of diabetes was 11.7±9.4 years. 45.5% of the patients were on insulin-therapy, 56% were on statins and 62.5% were on lowering-pressure therapy. The mean body mass index (BMI) was 32.9±6.7 kg/m2; the mean waist was 109.7±12.9 cm in men and 102.40±16.5 cm in women. (Table 1: baseline characteristics). 6.83% of patients achieved their HbA1c, LDLc and BP targets; 17.17% achieved their combined HbA1c and BP targets and 24.22% their HbA1c and LDL-c goals. Target HbA1c was met by 44.7% of patients. In conclusion, a high percentage of the patients treated by the Endocrine Department achieved an optimal glycaemic control (HbA1c≤7%). However, when BP and lipids were evaluated together this percentage dropped, despite the concomitant treatment with statins and lowering-pressure therapy. Therefore, the study shows that it is essential to intensify the treatment of type 2 diabetes patients, specially that one related to BP and lipids.

Article tools

My recent searches

No recent searches.