Endocrine Abstracts (2010) 22 P683

Visceral fat accumulation as a risk factor for the carotid plaque occurrence in ischemic stroke patients

Baburhan Guldiken1, Nermin Tuncbilek2, Sibel Guldiken3, Yavuz Durmus2, Remziye Hunkar1, Huseyin Ozdemir2, Mevlut Ture4, Nilda Turgut1 & Kemal Demir2

1Department of Neurology, Faculty of Medicine, Edirne, Turkey; 2Department of Radiology, Faculty of Medicine, Trakya University, Edirne, Turkey; 3Department of Endocrinology, Faculty of Medicine, Trakya University, Edirne, Turkey; 4Department of Biostatistics, Faculty of Medicine, Adnan Menderes University, Aydin, Turkey.

Aim: The present study aimed to investigate the relationship of visceral fat accumulation with the existence of the carotid plaque in ischemic stroke patients.

Materials and methods: Seventy patients (37 male, 33 female) with acute ischemic stroke were enrolled in the study. The carotid IMT and the existence of carotid plaque of the patients were evaluated by high resolution ultrasonography with a 7.5 MHz linear superficial array probe in B-mode. The abdominal fat areas (visceral and subcutaneous fat area) were measured by computed tomography scanning obtained at the umbilical level.

Results: A carotid plaque was detected in 31 of the patients, whereas 39 patients had no plaque. The mean visceral fat area was higher (P<0.05), and contrarily, the mean subcutaneous fat area was smaller (P<0.01) in carotid plaque positive patients than the negatives. The stroke subtypes showed no difference among two groups. Diabetes mellitus was more frequent in plaque positive patients (P<0.05).

Conclusion: Visceral fat accumulation contributes to the development of the carotid plaque in ischemic stroke patients.

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