Searchable abstracts of presentations at key conferences in endocrinology
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13th European Congress of Endocrinology


Management of phaechromocytoma

ea0026s24.1 | Management of phaechromocytoma | ECE2011

Biochemical screening for phaeochromocytoma using plasma free metanephrines: utility beyond diagnosis

Eisenhofer G

Measurements of plasma concentrations of the O-methylated metabolites of catecholamines including metanephrine, normetanephrine and methoxytyramine have advantages over other biochemical tests used to diagnose phaeochromocytoma for several reasons: i) the metabolites are produced within chromaffin cells continuously from catecholamines leaking from storage vesicles; ii) the single largest source of these metabolites is from adrenal medullary chromaffin cells, but this p...

ea0026s24.2 | Management of phaechromocytoma | ECE2011

Imaging of pheochromocytoma and paragangliomas

Timmers H J L M

The standard technique for the functional imaging of pheochromocytoma and paraganglioma (PPGL) is [123I]-metaiodobenzylguanidine single photon emission computed tomography (MIBG SPECT). However, metastases are more accurately detected by 2-[18F]-Fluoro-2-deoxy-D-glucose positron emission tomography (FDG PET). In a large prospective study of 216 patients evaluated at the NIH for benign or malignant PPGL, we investigated the sensitivity and specificity of FDG PET ...