Glycoregulation disorders in endocrine are frequently, hormone excess or deficit resulting for impaired metabolism of glucose by different mechanisms.
Methods: The study was conducted on 118 patients with hyperthyroidism, acromegaly and hypercortisolism. The inclusion criteria were: patients nondiagnostics that have not followed the treatment with drugs that could induce hyperglycemia (epinephrine, oral contraceptives, glucocorticoids, mineralcorticoids etc.), no-collateral family history of diabetes mellitus. Making glucose tolerance test with 75 g glucose pulvis with glucose assessment at 1 and 2 h after glucose ingestion, allowed in varying proportions the detection of diabetes mellitus in the study.
Results: Glycoregulation disorders were present in 58% of hyperthyroidism, 46% of patients with acromegaly, 53% of those with hyipercortisolism. Altered carbohydrate metabolism was directly proportional to the excess hormone level, on the types of diseases studied.
Conclusions: Differential treatment specific endocrine disease, improves the disorder of glycoregulation occurred in the context of hormonal dysfunction.
30 Apr - 04 May 2011
European Society of Endocrinology