Endocrine Abstracts (2011) 26 P59

Metabolic syndrome related to adrenal incidentaloma: observational study

Eduard Circo, Marian Beciu & Razvan Circo

‘Ovidius’ University, Constanta, CT, Romania.

Introduction: The adrenal incidentaloma is defined as a mass lesion found unexpectedly in an adrenal gland by an imaging procedure performed for another reason than suspected adrenal pathology.

Objective: To estimate the incidence of the adrenal mass and to define the algorithm for managing patients with incidental adrenal mass; a comparative analysis to the treatises data. The observational study was set one’s face towards by the adrenal incidental features who was diagnose between November 2008 and May 2010 and it was specificate the presence of some diseases proper to metabolic syndrome.

Methods: Were studied clinical historical of 34 patients (5 men and 29 women) with typical computed tomography features of adrenal mass. The structure of the patients batch with adrenal incidentaloma (n=34) was: batch A-nonsecretory tumors (n=21) (61.8%-TN) and batch B-secretor tumors (n=13) (38.2%-TS) whereby four patients with one-sided pheochromocytoma; five patients with Cushing syndrome; two patients with subclinical Cushing syndrome and two patients with adrenal hypertrophy.

Results: Overweight or obesity were found in 33.3% by batch A and 30.8% by batch B; hypertension in 61.9% by batch A and 69.2% by batch B; diabetes mellitus in 19% by batch A and 30.8% by batch B; dislipidemia in 42.9% by batch A and 30.8% by batch B; osteoporosis in 14.3% by batch A and 23.1% by batch B. Diameter was less then 4 cm in 85.7% by batch A and 36.5% by batch B of the tumors, and more than 4 cm in 14.3% by batch A and 63.5% by batch B. 90.5% by batch A and 76.9% by batch B were detected by computed tomography. Surgical adrenalectomy was performed in 69.2% TS and one TN with cyst character. Beside the histo-pathologic examination wherefore three carcinomas described by CT just two was confirmed, the other remains was adenomas (two pheochromo-cytoma and three cortisol secretor tumors) and one adrenal hypertrophy with cortisol secretion.

Conclusions: The tumor assess, the imagistic features and the quality of secretory/nonsecretory tumor is essential. Some features of the metabolic syndrome described to the patients with adrenal incidentalomas are enlarged the medically problem and it can form an argument to supplementary investigations.

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