Endocrine Abstracts (2011) 26 P670

Self-monitoring of blood glucose in type 2 diabetes mellitus: effect on glycemic control in non-insulin-treated patients

B Madeo1, S Scaltriti1, S Romano2, C Diazzi1, M El Goch2, A R M Granata1, E R Cavani2, C Carani1 & V Rochira1


1Chair and Unit of Endocrinology and Metabolism, Department of Medicine, Endocrinology and Metabolism, Geriatrics, NOCSAE of Baggiovara, University of Modena and Reggio Emilia, Modena, Italy; 2Unit of Diabetes Care, Department of Medicine, Endocrinology and Metabolism, Geriatrics, NOCSAE of Baggiovara, University of Modena and Reggio Emilia, Modena, Italy.


Introduction: The efficacy of self monitoring of blood glucose (SBMG) on glycaemic control in non-insulin-treated (NIT) type-2-diabetes-mellitus (T2DM) is still controversial. In this paper we evaluated the influence of SMBG on glycaemic control in patients with T2DM with poor glycaemic control treated with oral antidiabetic agents.

Methods: Thirty NIT-T2DM patients with poor glycaemic control and HbA1c>7% under treatment with oral hypoglycaemic agents attending our Diabetes Clinic were randomized as follows: SMBG Group (patients currently using SBMG without a previous training to interpret the result); Control Group (patients who were asked to increase the dosage at visit 1 for a better control of diabetes). The patients were evaluated after 3 and 6 months and HbA1c and fasting plasma glucose (FPG) were monitored. 15 subjects (7 females and 8 males) aged 65±7.7 years were randomized in the SMBG group and 15 (6 females and 9 males) aged 62.7±9.7 years in the control group.

Results: HbA1c levels significantly dropped after 3 (7.7±0.7%) and 6 (7.5±0.7%) months from baseline (8.4±0.6%) in the SMBG Group (P<0.001); HbA1c levels significantly dropped after 3 (8.0±1.1%) and 6 (7.7±1.0%) months from baseline (8.5±1.0) also in the control group (P<0.05) but without a significant difference between the two Groups when compared at the same time (3 or 6 months) of control. The FPG progressively decreased in both Groups in a significant way from baseline in SMBG group just after 3 months, while in the control group 6 months were necessary for reaching significance; no significant difference between the two groups was found when compared each other at 3 and 6 months.

Conclusions: The SMBG is as effective as increasing oral antidiabetic therapy dosage in improving the glycaemic control in NIT-T2DM subjects with previous poor glycaemic control even without a detailed training for interpreting the results.

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