ea0028s9.4 | Developmental programming of endocrine disease | SFEBES2012
, Nathanielsz Peter
Obesity and type II diabetes associated with obesity have reached epidemic proportions in both developed and underdeveloped countries. Epidemiological evidence has demonstrated that children born to obese women have a greater risk of developing obesity, insulin resistance and metabolic syndrome than those born to lean women. Leptin, an adipose tissue hormone, inhibits the brains central drive to eat, enabling maintenance of normal body weight and composition. In the rode...