Endocrine Abstracts

Bone’s ability to tolerate loading is determined by its material composition and structural design. During growth, growth plate trabeculae condense by appositional growth forming the metaphyseal cortices (‘corticalization’). Rapid distal radial longitudinal growth in early puberty outpaces trabecular condensation producing transitory intracortical porosity predisposing to fractures.In adulthood, remodeling removes and replaces damaged bone...