Searchable abstracts of presentations at key conferences in endocrinology
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15th International & 14th European Congress of Endocrinology

Symposia

Are endogenous testosterone levels predictors of cardiovascular events?

ea0029s27.1 | Are endogenous testosterone levels predictors of cardiovascular events? | ICEECE2012

Androgen action on the cardiovascular system

Channer K.

The most important cause of death as men age is cardiovascular disease and as men age so their androgen status declines. Studies have shown that lowering of endogenous androgen by deprivation therapy as treatment for prostate cancer increases the risk of cardiovascular death. In long term studies, low blood testosterone is associated with accelerated atherosclerosis as manifest in coronary, aortic and carotid vascular territories.Animal models of hypogon...

ea0029s27.3 | Are endogenous testosterone levels predictors of cardiovascular events? | ICEECE2012

Endogenous androgens, diabetes, and cardiovascular disease in women: the Rancho Bernardo study

Barrett-Connor E.

For >50 years female cardioprotection was attributed to premenopausal endogenous estrogen levels. We describe here how cardioprotection is greatly reduced in the presence of diabetes and endogenous testosterone levels.Forty years ago we measured total and bioavailable testosterone (bioT), total and bioavailable estradiol, and SHBG in community-dwelling older men and women from the Rancho Bernardo Study, using organic solvent extraction and celite col...