Searchable abstracts of presentations at key conferences in endocrinology
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15th European Congress of Endocrinology

Symposia

Action of glucocorticoids on bone

ea0032s8.1 | Action of glucocorticoids on bone | ECE2013

Glucocorticoid action on the skeleton

Tuckermann Jan

Glucorticoids (GCs) belong since their discovery to the standard therapy of rheumatoid arthritis (RA), a severe auto-inflammatory bone disease. One major side effect of GCs affects the skeleton itself leading to GC induced osteoporosis (GIO), the most secondary osteoporosis.To optimize anti-inflammatory therapies utilizing steroids a profound understanding of GC action on the interface of inflammation and skeletal integrity is required.<p class="abst...

ea0032s8.2 | Action of glucocorticoids on bone | ECE2013

Osteoporosis: now and the future

Hofbauer Lorenz C

Osteoporosis is an emerging medical and socioeconomic problem leading to fragility fractures, loss of mobility, chronic pain and cost to the individual and society. Diagnosis is often established only after fracture, although modern techniques exist to make the diagnosis early on where specific therapy is possible. Apart from calcium and vitamin D supplementation and lifestyle counseling, bisphosphonates have become the mainstay of therapy. However, long-term adherence with bi...

ea0032s8.3 | Action of glucocorticoids on bone | ECE2013

Glucocorticoid-induced osteoporosis

Compston J

Osteoporosis is a common complication of oral glucocorticoid therapy and is associated with significant morbidity. Glucocorticoid-induced osteoporosis is characterised by rapid bone loss and increased fracture risk during the first few months of therapy. The increase in fracture risk is dose-related and most prominent in the spine. Although awareness of glucocorticoid-induced osteoporosis has increased in recent years, the condition remains under-diagnosed and under-treated.</...