Endocrine Abstracts (2013) 32 P784 | DOI: 10.1530/endoabs.32.P784

PTH one year after gastric bypass in morbidly obese patients

Snezana Polovina1, Dragan Micic1, Jelena Gligorijevic2, Mirjana Sumarac-Dumanovic1, Goran Cvijovic1, Danica Stamenkovic-Pejkovic1, Jelena Milin1, Dusan Micic3 & Danka Jeremic1


1Clinic for Endocrinology, Diabetes and Diseases of Metabolism, Clinical Center of Serbia, Belgrade, Serbia; 2Dietary unit, Clinical Center of Serbia, Belgrade, Serbia; 3Emergency Center, Clinical Center of Serbia, Belgrade, Serbia.


Introduction: After gastric bypass, gastric secretion decreased and resorption of minerals and vitamins may be compromised. Lower resorpion of serum calcium and vitamin D could stimulate PTH secretion after restictive and malabsorptive bariatric procedures.

Methods: We have measured serum calcium, D vitamin and PTH in patients (n=50, 17 males and 33 females) 6 and 12 months after R en Y gastric bypass, 38.6±12.6 years of age, with BMI 43±9.2kg/m2. Exclusion criteria were thyroid dysfunction and previous primary or secondary osteoporosis. All patients were supplemented with calcium and vitamin D after bariatric surgery under the recommendations from European guideline for bariatric surgery. The supplements were contained 1250mg of calcium carbonate and 400IU of vitamin D in the first 2 months after surgery, and 600mg of calcium citrate and 200IU of vitamin D from the 3rd month to 1 year after gastric bypass.

Results: Serum calcium was 2.39±0.93mmol/l after 6 months and 2.41±0.10mmol/l after 12 months. The difference of −0.02mmol/l was no significant (P=0.83). The serum level of vitamin D was 53.79±24.60ng/ml after 6 months and 46.73±15.83ng/ml after 12 months. The difference of 7.02 was no significant (P=1.34). After 6 months the mean PTH was 56.288±25.429pg/ml, after 12 months 46.646±21.056pg/ml, and that difference also was no significant (P=0.94).

Conclusion: One year after gastric bypass there was no significant changes in serum calcium, vitamin D and PTH level. Dietary supplements with calcium carbonate and D vitamin in the first 2 months, and with calcium citrate and vitamine D after that period in obese patients after restrictive and malapsorptive bariatric surgery procedures, is sufficiant supplementation model without increasing PTH and risk for bone resorption.

Article tools

My recent searches

No recent searches.

My recently viewed abstracts